cholesterol sulfate

Cholesterol sulfate is a lipid of Sterol Lipids (ST) class. Cholesterol sulfate is associated with abnormalities such as Dental caries, Liver Cirrhosis, Ichthyosis, X-Linked, Retention hyperkeratosis and Dermatologic disorders. The involved functions are known as arachidonic acid metabolic process, Induced platelet aggregation, release of sequestered calcium ion into cytoplasm, Regulation and Platelet adhesion, function. Cholesterol sulfate often locates in Skin, Membrane, Body tissue, Human tissue and Tissue membrane. The associated genes with cholesterol sulfate are FAM3A gene, MMP gene, TSKU gene, FATE1 gene and TGM3 gene. The related lipids are Sterols, Steroids, Hydroxycholesterols, 7-dehydrocholesterol and Dehydrocholesterols.

References related to locations published in J. Biol. Chem.


PMIDJournalPublished DateAuthorTitle
18955490J. Biol. Chem.2008Higashi S et al.Identification of amino acid residues of matrix metalloproteinase-7 essential for binding to cholesterol sulfate.
20605794J. Biol. Chem.2010Yamamoto K et al.Cholesterol sulfate alters substrate preference of matrix metalloproteinase-7 and promotes degradations of pericellular laminin-332 and fibronectin.
16476739J. Biol. Chem.2006Yamamoto K et al.Binding of active matrilysin to cell surface cholesterol sulfate is essential for its membrane-associated proteolytic action and induction of homotypic cell adhesion.