stearic acid

stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.

References related to locations published in J. Biol. Chem.


PMIDJournalPublished DateAuthorTitle
9013572J. Biol. Chem.1997Paumen MB et al.Inhibition of carnitine palmitoyltransferase I augments sphingolipid synthesis and palmitate-induced apoptosis.
11567032J. Biol. Chem.2001Moon YA et al.Identification of a mammalian long chain fatty acyl elongase regulated by sterol regulatory element-binding proteins.
21697096J. Biol. Chem.2011Xu M et al.Novel functions of lipid-binding protein 5 in Caenorhabditis elegans fat metabolism.
23306194J. Biol. Chem.2013Lee W et al.Intracellular Mycobacterium tuberculosis exploits host-derived fatty acids to limit metabolic stress.
22194604J. Biol. Chem.2012Seeliger JC et al.Elucidation and chemical modulation of sulfolipid-1 biosynthesis in Mycobacterium tuberculosis.
20032470J. Biol. Chem.2010Collins JM et al.De novo lipogenesis and stearoyl-CoA desaturase are coordinately regulated in the human adipocyte and protect against palmitate-induced cell injury.
17416903J. Biol. Chem.2007Crunkhorn S et al.Peroxisome proliferator activator receptor gamma coactivator-1 expression is reduced in obesity: potential pathogenic role of saturated fatty acids and p38 mitogen-activated protein kinase activation.
17127673J. Biol. Chem.2007Sampath H et al.Stearoyl-CoA desaturase-1 mediates the pro-lipogenic effects of dietary saturated fat.
15277519J. Biol. Chem.2004Wong DA et al.Coordination of peroxisomal beta-oxidation and fatty acid elongation in HepG2 cells.
11423543J. Biol. Chem.2001Liang X et al.Heterogeneous fatty acylation of Src family kinases with polyunsaturated fatty acids regulates raft localization and signal transduction.
11085986J. Biol. Chem.2001Hannah VC et al.Unsaturated fatty acids down-regulate srebp isoforms 1a and 1c by two mechanisms in HEK-293 cells.