cholesterol is a lipid of Sterol Lipids (ST) class. Cholesterol is associated with abnormalities such as Trypanosomiasis, Chagas Disease, Cleft Palate, Chondrodysplasia punctata 2, X-linked dominant and Child syndrome. The involved functions are known as Blood Circulation, Sterol Biosynthesis Pathway, Receptor Mediated Endocytosis, Methylation and Signal. Cholesterol often locates in Animal tissue, Blood, Membrane, Plasma membrane and peroxisome. The associated genes with cholesterol are MBD2 gene, SIM, SLC33A1 gene, Genome and NSDHL gene. The related lipids are Sterols, zymosterol, fecosterol, Total cholesterol and 7-dehydrocholesterol. The related experimental models are Mouse Model, Knock-out, Genetically Engineered Mouse and Disease model.

References related to experimental models published in J. Biol. Chem.

PMIDJournalPublished DateAuthorTitle
11579092J. Biol. Chem.2001Leventhal AR et al.Acid sphingomyelinase-deficient macrophages have defective cholesterol trafficking and efflux.
11278882J. Biol. Chem.2001Han J et al.Oxidized low density lipoprotein decreases macrophage expression of scavenger receptor B-I.
20843794J. Biol. Chem.2010Johnston JB et al.Functional redundancy of steroid C26-monooxygenase activity in Mycobacterium tuberculosis revealed by biochemical and genetic analyses.
16844692J. Biol. Chem.2006Lebrun AH et al.Cloning of a cholesterol-alpha-glucosyltransferase from Helicobacter pylori.