PGD2
Pgd2 is a lipid of Fatty Acyls (FA) class. Pgd2 is associated with abnormalities such as Inflammatory disorder, Pleurisy, Rhinitis, Dehydration and Pneumonia. The involved functions are known as antagonists, fat cell differentiation, Phosphorylation, Process and Gene Expression. Pgd2 often locates in Cell surface, Body tissue, Extracellular, Bone Marrow and Membrane. The associated genes with PGD2 are oxytocin, 1-desamino-(O-Et-Tyr)(2)-, P4HTM gene, PTGS2 gene, PTGDS gene and IL3 gene. The related lipids are 15-deoxyprostaglandin J2, Nonesterified Fatty Acids, Lipopolysaccharides, Steroids and Liposomes. The related experimental models are Knock-out and Rodent Model.
References related to functions published in J. Immunol.
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 12707356 | J. Immunol. | 2003 | Heinemann A et al. | Delta 12-prostaglandin J2, a plasma metabolite of prostaglandin D2, causes eosinophil mobilization from the bone marrow and primes eosinophils for chemotaxis. |
| 12734337 | J. Immunol. | 2003 | Gosset P et al. | Prostaglandin D2 affects the maturation of human monocyte-derived dendritic cells: consequence on the polarization of naive Th cells. |
| 17709490 | J. Immunol. | 2007 | Chen Y et al. | Prostaglandin D2 suppresses human NK cell function via signaling through D prostanoid receptor. |
| 16081770 | J. Immunol. | 2005 | Chevalier E et al. | Cutting edge: chemoattractant receptor-homologous molecule expressed on Th2 cells plays a restricting role on IL-5 production and eosinophil recruitment. |
| 25681332 | J. Immunol. | 2015 | Maier NK et al. | The cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomes. |
| 25362177 | J. Immunol. | 2014 | Tsubosaka Y et al. | A deficiency in the prostaglandin D2 receptor CRTH2 exacerbates adjuvant-induced joint inflammation. |