LTC4

Ltc4 is a lipid of Fatty Acyls (FA) class. Ltc4 is associated with abnormalities such as Asthma, Eosinophilia, Pulmonary Eosinophilia, Pneumonia and Cardiovascular Diseases. The involved functions are known as Signal, Gene Expression, Stimulus, Signal Transduction and Metabolic Inhibition. Ltc4 often locates in Plasma membrane, Cytoplasm, Back, Cytoplasmic and Tissue membrane. The associated genes with LTC4 are STIM1 gene, ABCC2 gene, CD9 gene, Mutant Proteins and Amino Acids, Aromatic. The related lipids are glycolithocholate.

References related to functions published in J. Immunol.

PMID	Journal	Published Date	Author	Title
11490016	J. Immunol.	2001	Miura K et al.	Differences in functional consequences and signal transduction induced by IL-3, IL-5, and nerve growth factor in human basophils.
12646651	J. Immunol.	2003	Strait RT et al.	IL-4 exacerbates anaphylaxis.
10925305	J. Immunol.	2000	Eglite S et al.	Requirements for C5a receptor-mediated IL-4 and IL-13 production and leukotriene C4 generation in human basophils.
25904552	J. Immunol.	2015	Liu T et al.	Platelet-driven leukotriene C4-mediated airway inflammation in mice is aspirin-sensitive and depends on T prostanoid receptors.