Lipoxin A4

Lipoxin a4 is a lipid of Fatty Acyls (FA) class. Lipoxin a4 is associated with abnormalities such as Asthma, Cystic Fibrosis, Pneumonia, Obesity and Septicemia. The involved functions are known as Inflammation, Signal, Signal Transduction, Regulation and Metabolic Inhibition. Lipoxin a4 often locates in Immune system, Blood, soluble, Extracellular and Splenic Tissue. The associated genes with Lipoxin A4 are FPR2 gene, Homologous Gene, SAA1 gene, Trp-Lys-Tyr-Met-Val-Met and Annexin 1. The related lipids are Steroids. The related experimental models are Knock-out.

References related to functions published in J. Immunol.

PMID	Journal	Published Date	Author	Title
12218158	J. Immunol.	2002	Vaughn MW et al.	Identification, cloning, and functional characterization of a murine lipoxin A4 receptor homologue gene.
21398608	J. Immunol.	2011	Brancaleone V et al.	Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin A4 receptor and operative in the inflamed microvasculature.
23677469	J. Immunol.	2013	Xu Z et al.	Spontaneous miscarriages are explained by the stress/glucocorticoid/lipoxin A4 axis.
27742828	J. Immunol.	2016	Pazdrak K et al.	Cytokine-Induced Glucocorticoid Resistance from Eosinophil Activation: Protein Phosphatase 5 Modulation of Glucocorticoid Receptor Phosphorylation and Signaling.
26324767	J. Immunol.	2015	Gao Y et al.	Female-Specific Downregulation of Tissue Polymorphonuclear Neutrophils Drives Impaired Regulatory T Cell and Amplified Effector T Cell Responses in Autoimmune Dry Eye Disease.
26116507	J. Immunol.	2015	Fang X et al.	Human Mesenchymal Stem (Stromal) Cells Promote the Resolution of Acute Lung Injury in Part through Lipoxin A4.