Sphinganine

Sphinganine is a lipid of Sphingolipids (SP) class. Sphinganine is associated with abnormalities such as Sphingolipidoses, CLEFT LIP, CONGENITAL HEALED, Aortic aneurysm, familial thoracic 4, Morphologically altered structure and Atherosclerosis. The involved functions are known as Transcription, Genetic, Signal, Muscle Contraction, biological adaptation to stress and Gene Expression. Sphinganine often locates in Tissue membrane, Membrane, Protoplasm, Plasma membrane and Cytoplasmic. The associated genes with Sphinganine are SLC33A1 gene, HM13 gene, P4HTM gene, SPHK1 gene and SPHK2 gene. The related lipids are Sphingolipids, Phosphatidylserines, Sterols, Fatty Acids and inositolphosphorylceramide. The related experimental models are Mouse Model and Knock-out.

References related to abnormalities published in J. Lipid Res.


PMIDJournalPublished DateAuthorTitle
12897185J. Lipid Res.2003Lieser B et al.Quantification of sphingosine and sphinganine from crude lipid extracts by HPLC electrospray ionization tandem mass spectrometry.
19369694J. Lipid Res.2009Hu W et al.Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity.
16061940J. Lipid Res.2005Tani M et al.Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets.
20656918J. Lipid Res.2010Fukami H et al.Preparation of (13)C-labeled ceramide by acetic acid bacteria and its incorporation in mice.