Pristanic acid

Pristanic acid is a lipid of Prenol Lipids (PR) class. Pristanic acid is associated with abnormalities such as Refsum Disease, Peroxisomal Disorders, Hereditary Diseases, Peripheral Neuropathy and Sensory neuropathy. The involved functions are known as physiological aspects, Regulation, Pathogenesis, Oxidation and Peroxisome Proliferator-activated Receptor Activity [MoA]. Pristanic acid often locates in peroxisome, Body tissue, Mitochondria, Membrane of peroxisome and Organelles. The associated genes with Pristanic acid are PSG5 gene, LGALS4 gene, PEX2 gene, ACSL4 gene and ACSL1 Gene. The related lipids are pristanic acid, Fatty Acids, branched chain fatty acid, Plasmalogens and 3-hydroxypristanic acid.

References related to functions published in J. Lipid Res.


PMIDJournalPublished DateAuthorTitle
21521824J. Lipid Res.2011Zhao C et al.TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.
9469587J. Lipid Res.1998Verhoeven NM et al.Phytanic acid and pristanic acid are oxidized by sequential peroxisomal and mitochondrial reactions in cultured fibroblasts.
11060349J. Lipid Res.2000Zomer AW et al.Pristanic acid and phytanic acid: naturally occurring ligands for the nuclear receptor peroxisome proliferator-activated receptor alpha.
11060359J. Lipid Res.2000Ferdinandusse S et al.Subcellular localization and physiological role of alpha-methylacyl-CoA racemase.
9925655J. Lipid Res.1999Verhoeven NM et al.Analysis of pristanic acid beta-oxidation intermediates in plasma from healthy controls and patients affected with peroxisomal disorders by stable isotope dilution gas chromatography mass spectrometry.
20558530J. Lipid Res.2010Van Veldhoven PPBiochemistry and genetics of inherited disorders of peroxisomal fatty acid metabolism.