cholesterol sulfate

Cholesterol sulfate is a lipid of Sterol Lipids (ST) class. Cholesterol sulfate is associated with abnormalities such as Dental caries, Liver Cirrhosis, Ichthyosis, X-Linked, Retention hyperkeratosis and Dermatologic disorders. The involved functions are known as arachidonic acid metabolic process, Induced platelet aggregation, release of sequestered calcium ion into cytoplasm, Regulation and Platelet adhesion, function. Cholesterol sulfate often locates in Skin, Membrane, Body tissue, Human tissue and Tissue membrane. The associated genes with cholesterol sulfate are FAM3A gene, MMP gene, TSKU gene, FATE1 gene and TGM3 gene. The related lipids are Sterols, Steroids, Hydroxycholesterols, 7-dehydrocholesterol and Dehydrocholesterols.

References related to functions published in J. Lipid Res.


PMIDJournalPublished DateAuthorTitle
10588956J. Lipid Res.1999Bouwstra JA et al.Cholesterol sulfate and calcium affect stratum corneum lipid organization over a wide temperature range.
12730293J. Lipid Res.2003Strott CA and Higashi YCholesterol sulfate in human physiology: what's it all about?
18245815J. Lipid Res.2008Elias PM et al.Pathogenesis of permeability barrier abnormalities in the ichthyoses: inherited disorders of lipid metabolism.
16825673J. Lipid Res.2006Jiang YJ et al.Regulation of ABCA1 expression in human keratinocytes and murine epidermis.
16150827J. Lipid Res.2005Jiang YJ et al.LXR and PPAR activators stimulate cholesterol sulfotransferase type 2 isoform 1b in human keratinocytes.
25502769J. Lipid Res.2015Sánchez-Guijo A et al.High levels of oxysterol sulfates in serum of patients with steroid sulfatase deficiency.