DHA

Dha is a lipid of Fatty Acyls (FA) class. Dha is associated with abnormalities such as Atherosclerosis, Consumption-archaic term for TB, Chronic disease, Cardiovascular Diseases and Diabetes Mellitus, Non-Insulin-Dependent. The involved functions are known as Inflammation, Oxidation, fatty acid oxidation, Fatty Acid Metabolism and Lipid Metabolism. Dha often locates in Hepatic, Protoplasm, Mucous Membrane, Epithelium and outer membrane. The associated genes with DHA are IMPACT gene, FATE1 gene, GAPDH gene, THOC4 gene and SLC33A1 gene. The related lipids are stearidonic acid, Fatty Acids, Total cholesterol, Lipopolysaccharides and Dietary Fatty Acid. The related experimental models are Mouse Model, Transgenic Model, Animal Disease Models and Arthritis, Experimental.

References related to functions published in J. Lipid Res.

PMID	Journal	Published Date	Author	Title
9548590	J. Lipid Res.	1998	Madsen L et al.	Docosahexaenoic and eicosapentaenoic acids are differently metabolized in rat liver during mitochondria and peroxisome proliferation.
9555950	J. Lipid Res.	1998	Bechoua S et al.	Docosahexaenoic acid lowers phosphatidate level in human activated lymphocytes despite phospholipase D activation.
9684743	J. Lipid Res.	1998	Connor WE et al.	Uneven distribution of desmosterol and docosahexaenoic acid in the heads and tails of monkey sperm.
11254745	J. Lipid Res.	2001	Pound EM et al.	Partitioning of polyunsaturated fatty acids, which prevent cardiac arrhythmias, into phospholipid cell membranes.
12923230	J. Lipid Res.	2003	Heath RB et al.	Selective partitioning of dietary fatty acids into the VLDL TG pool in the early postprandial period.
10681400	J. Lipid Res.	2000	Calviello G et al.	n-3 PUFA dietary supplementation inhibits proliferation and store-operated calcium influx in thymoma cells growing in Balb/c mice.
21296957	J. Lipid Res.	2011	Stephensen CB et al.	ALOX5 gene variants affect eicosanoid production and response to fish oil supplementation.
19023138	J. Lipid Res.	2009	Tanito M et al.	High levels of retinal membrane docosahexaenoic acid increase susceptibility to stress-induced degeneration.
19018037	J. Lipid Res.	2009	Bazan NG	Neuroprotectin D1-mediated anti-inflammatory and survival signaling in stroke, retinal degenerations, and Alzheimer's disease.
19571329	J. Lipid Res.	2009	Gao F et al.	Whole-body synthesis secretion of docosahexaenoic acid from circulating eicosapentaenoic acid in unanesthetized rats.
20382842	J. Lipid Res.	2010	Bazan NG et al.	Rescue and repair during photoreceptor cell renewal mediated by docosahexaenoic acid-derived neuroprotectin D1.
20664072	J. Lipid Res.	2010	Morisseau C et al.	Naturally occurring monoepoxides of eicosapentaenoic acid and docosahexaenoic acid are bioactive antihyperalgesic lipids.
16582421	J. Lipid Res.	2006	Kawai Y et al.	Formation of Nepsilon-(succinyl)lysine in vivo: a novel marker for docosahexaenoic acid-derived protein modification.
22095831	J. Lipid Res.	2012	Njoroge SW et al.	DHA and EPA reverse cystic fibrosis-related FA abnormalities by suppressing FA desaturase expression and activity.
15627650	J. Lipid Res.	2005	Denys A et al.	n-3 PUFAs modulate T-cell activation via protein kinase C-alpha and -epsilon and the NF-kappaB signaling pathway.
16899822	J. Lipid Res.	2006	Butovich IA et al.	Dihydroxydocosahexaenoic acids of the neuroprotectin D family: synthesis, structure, and inhibition of human 5-lipoxygenase.
16150835	J. Lipid Res.	2005	Butovich IA	On the structure and synthesis of neuroprotectin D1, a novel anti-inflammatory compound of the docosahexaenoic acid family.
18503030	J. Lipid Res.	2008	Farias SE et al.	Formation of eicosanoids, E2/D2 isoprostanes, and docosanoids following decapitation-induced ischemia, measured in high-energy-microwaved rat brain.
22315394	J. Lipid Res.	2012	Rockett BD et al.	Fish oil increases raft size and membrane order of B cells accompanied by differential effects on function.
23471029	J. Lipid Res.	2013	Dobson EP et al.	Controlled formation of mono- and dihydroxy-resolvins from EPA and DHA using soybean 15-lipoxygenase.
23349208	J. Lipid Res.	2013	Jaudszus A et al.	Evaluation of suppressive and pro-resolving effects of EPA and DHA in human primary monocytes and T-helper cells.
23160180	J. Lipid Res.	2013	Al-Hilal M et al.	Genetic variation at the FADS1-FADS2 gene locus influences delta-5 desaturase activity and LC-PUFA proportions after fish oil supplement.