lanosterol
lanosterol is a lipid of Sterol Lipids (ST) class. Lanosterol is associated with abnormalities such as Infection, Atherosclerosis, Myocardial Infarction, Chagas Disease and Fatty Liver. The involved functions are known as Signal, Cytokinesis, physiological aspects, Stereochemistry and ergosterol biosynthetic process. Lanosterol often locates in Body tissue, Membrane, Plasma membrane, Tissue membrane and Cytoskeletal Filaments. The associated genes with lanosterol are Retinoic Acid Response Element, P4HTM gene, CYP51A1 gene, HM13 gene and SC4MOL gene. The related lipids are pneumocysterol, Sterols, lanosteryl acetate, ebericol and cycloartenol. The related experimental models are Knock-out.
References related to genes published in J. Lipid Res.
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 11254746 | J. Lipid Res. | 2001 | Méjanelle L et al. | Ergosterol biosynthesis in novel melanized fungi from hypersaline environments. |
| 22135275 | J. Lipid Res. | 2012 | Hargrove TY et al. | Structural complex of sterol 14α-demethylase (CYP51) with 14α-methylenecyclopropyl-Delta7-24, 25-dihydrolanosterol. |
| 23509403 | J. Lipid Res. | 2013 | Keber R et al. | Male germ cell-specific knockout of cholesterogenic cytochrome P450 lanosterol 14α-demethylase (Cyp51). |
| 22517925 | J. Lipid Res. | 2012 | McDonald JG et al. | A comprehensive method for extraction and quantitative analysis of sterols and secosteroids from human plasma. |
| 20574076 | J. Lipid Res. | 2010 | Andreyev AY et al. | Subcellular organelle lipidomics in TLR-4-activated macrophages. |
| 27313059 | J. Lipid Res. | 2016 | Hargrove TY et al. | Human sterol 14α-demethylase as a target for anticancer chemotherapy: towards structure-aided drug design. |