lysophosphatidic acid

lysophosphatidic acid is a lipid of Glycerophospholipids (GP) class. Lysophosphatidic acid is associated with abnormalities such as Atherosclerosis, Alzheimer's Disease, Asthma, Diabetes Mellitus, Non-Insulin-Dependent and Septicemia. The involved functions are known as Inflammation, Chemotaxis, Binding (Molecular Function), Polymerization and Inflammatory Response. Lysophosphatidic acid often locates in Cytoskeleton, Microfilaments, actin cytoskeleton, Extracellular and Structure of germinal center of lymph node. The associated genes with lysophosphatidic acid are TNF gene, MAPK3 gene, RHOA gene, CDC42 gene and ADRBK1 gene. The related lipids are lysophosphatidic acid, Lipopolysaccharides, Lysophosphatidylcholines, Lysophospholipids and Phosphatidic Acid. The related experimental models are Knock-out, Transgenic Model, Rodent Model and Disease model.

References related to genes published in J. Lipid Res.


PMIDJournalPublished DateAuthorTitle
28143894J. Lipid Res.2017Emoto S et al.Analysis of glycero-lysophospholipids in gastric cancerous ascites.
27444045J. Lipid Res.2016Fleming JK et al.A novel approach for measuring sphingosine-1-phosphate and lysophosphatidic acid binding to carrier proteins using monoclonal antibodies and the Kinetic Exclusion Assay.
25210149J. Lipid Res.2014Tang X et al.Lipid phosphate phosphatase-1 expression in cancer cells attenuates tumor growth and metastasis in mice.
24652606J. Lipid Res.2014Chun JAn introduction to the Journal of Lipid Research Thematic Series on lysophospholipids.