Platelet activating factor

Platelet activating factor is a lipid of Glycerophospholipids (GP) class. Platelet activating factor is associated with abnormalities such as Atherosclerosis, Acute cholecystitis without calculus, Cholecystitis, Colitis and Cholecystitis, Acute. The involved functions are known as Cell Survival, Metabolic Inhibition, lipid oxidation, Apoptosis and Oxidation. Platelet activating factor often locates in soluble, Cellular Membrane, Smooth muscle (tissue), Intima and Tissue specimen. The associated genes with Platelet activating factor are apolipoprotein A-I Milano, Homologous Gene, TSPO gene, HBEGF gene and SLC33A1 gene. The related lipids are Hydroxycholesterols, Liposomes, 25-hydroxycholesterol, Lysophosphatidylcholines and Lipopolysaccharides. The related experimental models are Knock-out, Mouse Model and Transgenic Model.

References related to lipids published in J. Lipid Res.

PMID	Journal	Published Date	Author	Title
9643362	J. Lipid Res.	1998	Botitsi E et al.	Metabolic fate of platelet-activating factor (PAF, 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) and lyso-PAF (1-O-alkyl-2-lyso-sn-glycero-3-phosphocholine) in FRTL5 cells.
11518762	J. Lipid Res.	2001	Marathe GK et al.	Lysophosphatidylcholine and lyso-PAF display PAF-like activity derived from contaminating phospholipids.
11290831	J. Lipid Res.	2001	Marathe GK et al.	Identification of platelet-activating factor as the inflammatory lipid mediator in CCl4-metabolizing rat liver.
15520455	J. Lipid Res.	2005	Owen JS et al.	An improved assay for platelet-activating factor using HPLC-tandem mass spectrometry.
15995176	J. Lipid Res.	2005	Androulakis N et al.	Molecular and mechanistic characterization of platelet-activating factor-like bioactivity produced upon LDL oxidation.
18550892	J. Lipid Res.	2008	Ryan SD et al.	Heterogeneity in the sn-1 carbon chain of platelet-activating factor glycerophospholipids determines pro- or anti-apoptotic signaling in primary neurons.