Lysophosphatidylcholine

Lysophosphatidylcholine is a lipid of Glycerophospholipids (GP) class. Lysophosphatidylcholine is associated with abnormalities such as Ischemia, Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Fatty Liver and Atherosclerosis. The involved functions are known as Inflammation, antagonists, Signal Transduction, Signal Pathways and Saturated. Lysophosphatidylcholine often locates in Body tissue, Head, integral to membrane, Membrane and Extracellular. The associated genes with Lysophosphatidylcholine are RHOA gene, Homologous Gene, GPR4 gene, GPR68 gene and TRPV2 gene. The related lipids are Nonesterified Fatty Acids, lysophosphatidylethanolamine, Lysophosphatidylcholines, Phosphatidylserines and 25-hydroxycholesterol. The related experimental models are Knock-out and Disease model.

References related to lipids published in J. Lipid Res.

PMID	Journal	Published Date	Author	Title
25510248	J. Lipid Res.	2015	Takahashi H et al.	Metabolomics reveal 1-palmitoyl lysophosphatidylcholine production by peroxisome proliferator-activated receptor α.
26965826	J. Lipid Res.	2016	Chattopadhyay A et al.	Tg6F ameliorates the increase in oxidized phospholipids in the jejunum of mice fed unsaturated LysoPC or WD.
26839333	J. Lipid Res.	2016	Fernandez-Ruiz I et al.	Differential lipid metabolism in monocytes and macrophages: influence of cholesterol loading.
26830860	J. Lipid Res.	2016	Fisher AB et al.	A novel lysophosphatidylcholine acyl transferase activity is expressed by peroxiredoxin 6.
20610733	J. Lipid Res.	2010	Riederer M et al.	Acyl chain-dependent effect of lysophosphatidylcholine on endothelial prostacyclin production.
19458387	J. Lipid Res.	2009	Testerink N et al.	Depletion of phosphatidylcholine affects endoplasmic reticulum morphology and protein traffic at the Golgi complex.
17951222	J. Lipid Res.	2008	Han MS et al.	Lysophosphatidylcholine as a death effector in the lipoapoptosis of hepatocytes.
17395985	J. Lipid Res.	2007	Lessig J et al.	Hypochlorous acid-mediated generation of glycerophosphocholine from unsaturated plasmalogen glycerophosphocholine lipids.
16607035	J. Lipid Res.	2006	Guillaume C et al.	Interplay between lipoproteins and bee venom phospholipase A2 in relation to their anti-Plasmodium toxicity.
15772425	J. Lipid Res.	2005	Fisher AB et al.	Altered lung phospholipid metabolism in mice with targeted deletion of lysosomal-type phospholipase A2.
12032165	J. Lipid Res.	2002	Gesta S et al.	Secretion of a lysophospholipase D activity by adipocytes: involvement in lysophosphatidic acid synthesis.
11518771	J. Lipid Res.	2001	Schiller J et al.	Lipid analysis of human HDL and LDL by MALDI-TOF mass spectrometry and (31)P-NMR.
10508201	J. Lipid Res.	1999	Golfman LS et al.	Lysophosphatidylcholine induces arachidonic acid release and calcium overload in cardiac myoblastic H9c2 cells.