Cholic acid

Cholic acid is a lipid of Sterol Lipids (ST) class. Cholic acid is associated with abnormalities such as Cholestasis, Intrahepatic Cholestasis, Atherosclerosis, Diabetes and cholesterol gallstones. The involved functions are known as Homeostasis, Enterohepatic Circulation, Proliferation (morphologic abnormality), Process and Cell Proliferation. Cholic acid often locates in Hepatic, Cytoplasmic matrix, Membrane, Protoplasm and Tissue membrane. The associated genes with Cholic acid are CYP27A1 gene, ABCB11 gene, NR5A2 gene, SLC10A2 gene and SLC10A1 gene. The related lipids are ursocholic acid, Steroids, Cholestenes, Cholestanes and cholanic acid.

References related to lipids published in J. Lipid Res.


PMIDJournalPublished DateAuthorTitle
13130122J. Lipid Res.2004Fujino T et al.Structure-activity relationship of bile acids and bile acid analogs in regard to FXR activation.
20671298J. Lipid Res.2010Zhang Y and Klaassen CDEffects of feeding bile acids and a bile acid sequestrant on hepatic bile acid composition in mice.
17332599J. Lipid Res.2007Cuesta de Juan S et al.Ontogenic development-associated changes in the expression of genes involved in rat bile acid homeostasis.
22021638J. Lipid Res.2012Ridlon JM and Hylemon PBIdentification and characterization of two bile acid coenzyme A transferases from Clostridium scindens, a bile acid 7α-dehydroxylating intestinal bacterium.