Lysophosphatidylcholine
Lysophosphatidylcholine is a lipid of Glycerophospholipids (GP) class. Lysophosphatidylcholine is associated with abnormalities such as Ischemia, Obesity, Diabetes Mellitus, Non-Insulin-Dependent, Fatty Liver and Atherosclerosis. The involved functions are known as Inflammation, antagonists, Signal Transduction, Signal Pathways and Saturated. Lysophosphatidylcholine often locates in Body tissue, Head, integral to membrane, Membrane and Extracellular. The associated genes with Lysophosphatidylcholine are RHOA gene, Homologous Gene, GPR4 gene, GPR68 gene and TRPV2 gene. The related lipids are Nonesterified Fatty Acids, lysophosphatidylethanolamine, Lysophosphatidylcholines, Phosphatidylserines and 25-hydroxycholesterol. The related experimental models are Knock-out and Disease model.
References related to locations published in J. Lipid Res.
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 27049024 | J. Lipid Res. | 2016 | Hirsova P et al. | Lipotoxic lethal and sublethal stress signaling in hepatocytes: relevance to NASH pathogenesis. |
| 26839333 | J. Lipid Res. | 2016 | Fernandez-Ruiz I et al. | Differential lipid metabolism in monocytes and macrophages: influence of cholesterol loading. |
| 26830860 | J. Lipid Res. | 2016 | Fisher AB et al. | A novel lysophosphatidylcholine acyl transferase activity is expressed by peroxiredoxin 6. |
| 25713101 | J. Lipid Res. | 2015 | Siddiqi S and Mansbach CM | Dietary and biliary phosphatidylcholine activates PKCζ in rat intestine. |
| 21908646 | J. Lipid Res. | 2011 | Hollie NI and Hui DY | Group 1B phospholipase A₂ deficiency protects against diet-induced hyperlipidemia in mice. |
| 21447485 | J. Lipid Res. | 2011 | Han MS et al. | Lysophosphatidylcholine as an effector of fatty acid-induced insulin resistance. |
| 19805624 | J. Lipid Res. | 2010 | Yang X et al. | Secretory phospholipase A2 type III enhances alpha-secretase-dependent amyloid precursor protein processing through alterations in membrane fluidity. |
| 19458387 | J. Lipid Res. | 2009 | Testerink N et al. | Depletion of phosphatidylcholine affects endoplasmic reticulum morphology and protein traffic at the Golgi complex. |
| 16607035 | J. Lipid Res. | 2006 | Guillaume C et al. | Interplay between lipoproteins and bee venom phospholipase A2 in relation to their anti-Plasmodium toxicity. |
| 11861673 | J. Lipid Res. | 2002 | Tokumura A et al. | Increased formation of lysophosphatidic acids by lysophospholipase D in serum of hypercholesterolemic rabbits. |
| 10508201 | J. Lipid Res. | 1999 | Golfman LS et al. | Lysophosphatidylcholine induces arachidonic acid release and calcium overload in cardiac myoblastic H9c2 cells. |
| 10357830 | J. Lipid Res. | 1999 | Gómez-Muñoz A et al. | Lysophosphatidylcholine stimulates phospholipase D activity in mouse peritoneal macrophages. |