Sphinganine
Sphinganine is a lipid of Sphingolipids (SP) class. Sphinganine is associated with abnormalities such as Sphingolipidoses, CLEFT LIP, CONGENITAL HEALED, Aortic aneurysm, familial thoracic 4, Morphologically altered structure and Atherosclerosis. The involved functions are known as Transcription, Genetic, Signal, Muscle Contraction, biological adaptation to stress and Gene Expression. Sphinganine often locates in Tissue membrane, Membrane, Protoplasm, Plasma membrane and Cytoplasmic. The associated genes with Sphinganine are SLC33A1 gene, HM13 gene, P4HTM gene, SPHK1 gene and SPHK2 gene. The related lipids are Sphingolipids, Phosphatidylserines, Sterols, Fatty Acids and inositolphosphorylceramide. The related experimental models are Mouse Model and Knock-out.
References related to locations published in J. Lipid Res.
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
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| 12777464 | J. Lipid Res. | 2003 | Dragusin M et al. | Metabolism of the unnatural anticancer lipid safingol, L-threo-dihydrosphingosine, in cultured cells. |
| 19369694 | J. Lipid Res. | 2009 | Hu W et al. | Palmitate increases sphingosine-1-phosphate in C2C12 myotubes via upregulation of sphingosine kinase message and activity. |
| 16061940 | J. Lipid Res. | 2005 | Tani M et al. | Mechanisms of sphingosine and sphingosine 1-phosphate generation in human platelets. |
| 22661289 | J. Lipid Res. | 2012 | Kim HJ et al. | A fluorescent assay for ceramide synthase activity. |
| 20656918 | J. Lipid Res. | 2010 | Fukami H et al. | Preparation of (13)C-labeled ceramide by acetic acid bacteria and its incorporation in mice. |
| 19786568 | J. Lipid Res. | 2010 | Park H et al. | Transcript profiling and lipidomic analysis of ceramide subspecies in mouse embryonic stem cells and embryoid bodies. |
| 20660127 | J. Lipid Res. | 2010 | Hammad SM et al. | Blood sphingolipidomics in healthy humans: impact of sample collection methodology. |
| 18359959 | J. Lipid Res. | 2008 | Masukawa Y et al. | Characterization of overall ceramide species in human stratum corneum. |
| 18263851 | J. Lipid Res. | 2008 | Oda M et al. | The relationship between the metabolism of sphingomyelin species and the hemolysis of sheep erythrocytes induced by Clostridium perfringens alpha-toxin. |
| 16639079 | J. Lipid Res. | 2006 | Masukawa Y et al. | Liquid chromatography-mass spectrometry for comprehensive profiling of ceramide molecules in human hair. |
| 12639977 | J. Lipid Res. | 2003 | Hoekstra D et al. | Membrane dynamics and cell polarity: the role of sphingolipids. |