Cholic acid

Cholic acid is a lipid of Sterol Lipids (ST) class. Cholic acid is associated with abnormalities such as Cholestasis, Intrahepatic Cholestasis, Atherosclerosis, Diabetes and cholesterol gallstones. The involved functions are known as Homeostasis, Enterohepatic Circulation, Proliferation (morphologic abnormality), Process and Cell Proliferation. Cholic acid often locates in Hepatic, Cytoplasmic matrix, Membrane, Protoplasm and Tissue membrane. The associated genes with Cholic acid are CYP27A1 gene, ABCB11 gene, NR5A2 gene, SLC10A2 gene and SLC10A1 gene. The related lipids are ursocholic acid, Steroids, Cholestenes, Cholestanes and cholanic acid.

References related to locations published in J. Lipid Res.


PMIDJournalPublished DateAuthorTitle
16269825J. Lipid Res.2006Shih DM et al.A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids.
22021638J. Lipid Res.2012Ridlon JM and Hylemon PBIdentification and characterization of two bile acid coenzyme A transferases from Clostridium scindens, a bile acid 7α-dehydroxylating intestinal bacterium.
20847296J. Lipid Res.2010Volynets V et al.Protective effect of bile acids on the onset of fructose-induced hepatic steatosis in mice.