7-Dehydrocholesterol is a lipid of Sterol Lipids (ST) class. 7-dehydrocholesterol is associated with abnormalities such as Dehydration, Exanthema, RETINITIS PIGMENTOSA 49, Congenital Abnormality and Failure to Thrive. The involved functions are known as 5-(carboxyamino)imidazole ribonucleotide mutase activity, Mutation, Lysis, Anabolism and Biosynthetic Pathways. 7-dehydrocholesterol often locates in Plasma membrane, Body tissue, Tissue membrane, Membrane and outer membrane. The associated genes with 7-Dehydrocholesterol are mutant gene, THEMIS gene, IGKV1D-37 gene, LGALS4 gene and Orthologous Gene. The related lipids are Membrane Lipids, Steroids, Sterols, campesterol and 7-dehydrocholesterol. The related experimental models are Mouse Model, Knock-out and Rodent Model.
PMID | Journal | Published Date | Author | Title |
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21402677 | J. Lipid Res. | 2011 | Xu L et al. | An oxysterol biomarker for 7-dehydrocholesterol oxidation in cell/mouse models for Smith-Lemli-Opitz syndrome. |
23381570 | J. Lipid Res. | 2013 | Xu L et al. | Metabolism of oxysterols derived from nonenzymatic oxidation of 7-dehydrocholesterol in cells. |
25017465 | J. Lipid Res. | 2014 | Goyal S et al. | Oxidation of 7-dehydrocholesterol and desmosterol by human cytochrome P450 46A1. |
14594996 | J. Lipid Res. | 2004 | Keller RK et al. | Formation of 7-dehydrocholesterol-containing membrane rafts in vitro and in vivo, with relevance to the Smith-Lemli-Opitz syndrome. |