Ganglioside GM2
Ganglioside GM2 is a lipid of Sphingolipids (SP) class. Ganglioside gm2 is associated with abnormalities such as Sensory neuropathy, Neuropathy, Autoimmune Diseases, Polyradiculoneuropathy, Chronic Inflammatory Demyelinating and Neuromuscular Diseases. The involved functions are known as Pressure- physical agent, Cytolysis, Inflammation, Complement-Dependent Cytotoxicity and conjugation. Ganglioside gm2 often locates in Membrane, Entire nervous system, Cell surface, Biopsy sample and Lipid Bilayers. The associated genes with Ganglioside GM2 are anti-IgM, Polypeptides, Transgenes, Alleles and Homologous Gene. The related lipids are Ganglioside GA2, QS 21, sulfate-3-glucuronyl paragloboside, Lipopolysaccharides and IV(4)-galactosyl-N-acetylganglioside GD1a. The related experimental models are Disease model.
References related to abnormalities published in J. Neurol. Sci.
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 15850580 | J. Neurol. Sci. | 2005 | Usuki S et al. | AIDP and CIDP having specific antibodies to the carbohydrate epitope (-NeuAcalpha2-8NeuAcalpha2-3Galbeta1-4Glc-) of gangliosides. |
| 17915254 | J. Neurol. Sci. | 2008 | Nobile-Orazio E et al. | How useful are anti-neural IgM antibodies in the diagnosis of chronic immune-mediated neuropathies? |
| 15465085 | J. Neurol. Sci. | 2004 | Kunishige M et al. | Isolated cranial neuropathy associated with anti-glycolipid antibodies. |
| 7595635 | J. Neurol. Sci. | 1995 | Matsumoto A et al. | Ganglioside characterization of a cell line displaying motor neuron-like phenotype: GM2 as a possible major ganglioside in motor neurons. |