quercetin is a lipid of Polyketides (PK) class. Quercetin is associated with abnormalities such as Coronary heart disease, Myocardial Infarction, Cirrhosis, Coronary Arteriosclerosis and Vascular ring. The involved functions are known as Vasodilation, physiological aspects, Fermentation, Process and Ingredient. Quercetin often locates in Arterial system, Endothelium, Skin, Endothelium, Vascular and Tissue specimen. The associated genes with quercetin are P4HTM gene, SULT gene, UGT1A1 gene, ARHGAP26 gene and PLXNB1 gene. The related lipids are blood lipid, Promega, Steroids, Phosphatidylserines and Fatty Acids. The related experimental models are Knock-out, Mouse Model, Xenograft Model, Tissue Model and Cancer Model.
PMID | Journal | Published Date | Author | Title |
---|---|---|---|---|
9482769 | J. Nutr. | 1998 | Conquer JA et al. | Supplementation with quercetin markedly increases plasma quercetin concentration without effect on selected risk factors for heart disease in healthy subjects. |
11238754 | J. Nutr. | 2001 | de Vries JH et al. | Red wine is a poor source of bioavailable flavonols in men. |
11823574 | J. Nutr. | 2002 | DuPont MS et al. | Polyphenols from alcoholic apple cider are absorbed, metabolized and excreted by humans. |
11435510 | J. Nutr. | 2001 | Sesink AL et al. | Quercetin glucuronides but not glucosides are present in human plasma after consumption of quercetin-3-glucoside or quercetin-4'-glucoside. |
12612140 | J. Nutr. | 2003 | Pal S et al. | Red wine polyphenolics increase LDL receptor expression and activity and suppress the secretion of ApoB100 from human HepG2 cells. |
12888656 | J. Nutr. | 2003 | Mertens-Talcott SU et al. | Low concentrations of quercetin and ellagic acid synergistically influence proliferation, cytotoxicity and apoptosis in MOLT-4 human leukemia cells. |
10801919 | J. Nutr. | 2000 | Olthof MR et al. | Bioavailabilities of quercetin-3-glucoside and quercetin-4'-glucoside do not differ in humans. |
10958819 | J. Nutr. | 2000 | Arai Y et al. | Dietary intakes of flavonols, flavones and isoflavones by Japanese women and the inverse correlation between quercetin intake and plasma LDL cholesterol concentration. |
21562239 | J. Nutr. | 2011 | Cuevas MJ et al. | Suppression of amphiregulin/epidermal growth factor receptor signals contributes to the protective effects of quercetin in cirrhotic rats. |
19056647 | J. Nutr. | 2009 | Warren CA et al. | Quercetin may suppress rat aberrant crypt foci formation by suppressing inflammatory mediators that influence proliferation and apoptosis. |
19494027 | J. Nutr. | 2009 | Tieppo J et al. | Quercetin administration ameliorates pulmonary complications of cirrhosis in rats. |
20032478 | J. Nutr. | 2010 | Egert S et al. | Serum lipid and blood pressure responses to quercetin vary in overweight patients by apolipoprotein E genotype. |
17951477 | J. Nutr. | 2007 | Edwards RL et al. | Quercetin reduces blood pressure in hypertensive subjects. |
17449583 | J. Nutr. | 2007 | Ruiz PA et al. | Quercetin inhibits TNF-induced NF-kappaB transcription factor recruitment to proinflammatory gene promoters in murine intestinal epithelial cells. |
17311951 | J. Nutr. | 2007 | Carlstrom J et al. | A quercetin supplemented diet does not prevent cardiovascular complications in spontaneously hypertensive rats. |
18424596 | J. Nutr. | 2008 | Wiczkowski W et al. | Quercetin from shallots (Allium cepa L. var. aggregatum) is more bioavailable than its glucosides. |
15795425 | J. Nutr. | 2005 | Enkhmaa B et al. | Mulberry (Morus alba L.) leaves and their major flavonol quercetin 3-(6-malonylglucoside) attenuate atherosclerotic lesion development in LDL receptor-deficient mice. |
16365056 | J. Nutr. | 2006 | Graf BA et al. | Rat gastrointestinal tissues metabolize quercetin. |
14988445 | J. Nutr. | 2004 | de Pascual-Teresa S et al. | Quercetin metabolites downregulate cyclooxygenase-2 transcription in human lymphocytes ex vivo but not in vivo. |
15930438 | J. Nutr. | 2005 | Martínez-Flórez S et al. | Quercetin attenuates nuclear factor-kappaB activation and nitric oxide production in interleukin-1beta-activated rat hepatocytes. |
15987855 | J. Nutr. | 2005 | de Boer VC et al. | Tissue distribution of quercetin in rats and pigs. |
17056814 | J. Nutr. | 2006 | Dihal AA et al. | Quercetin, but not its glycosidated conjugate rutin, inhibits azoxymethane-induced colorectal carcinogenesis in F344 rats. |
16177186 | J. Nutr. | 2005 | Dias AS et al. | Quercetin decreases oxidative stress, NF-kappaB activation, and iNOS overexpression in liver of streptozotocin-induced diabetic rats. |
18492835 | J. Nutr. | 2008 | Amasheh M et al. | Quercetin enhances epithelial barrier function and increases claudin-4 expression in Caco-2 cells. |
22535755 | J. Nutr. | 2012 | Panchal SK et al. | Quercetin ameliorates cardiovascular, hepatic, and metabolic changes in diet-induced metabolic syndrome in rats. |
22915297 | J. Nutr. | 2012 | Marcolin E et al. | Quercetin treatment ameliorates inflammation and fibrosis in mice with nonalcoholic steatohepatitis. |