quercetin

quercetin is a lipid of Polyketides (PK) class. Quercetin is associated with abnormalities such as Coronary heart disease, Myocardial Infarction, Cirrhosis, Coronary Arteriosclerosis and Vascular ring. The involved functions are known as Vasodilation, physiological aspects, Fermentation, Process and Ingredient. Quercetin often locates in Arterial system, Endothelium, Skin, Endothelium, Vascular and Tissue specimen. The associated genes with quercetin are P4HTM gene, SULT gene, UGT1A1 gene, ARHGAP26 gene and PLXNB1 gene. The related lipids are blood lipid, Promega, Steroids, Phosphatidylserines and Fatty Acids. The related experimental models are Knock-out, Mouse Model, Xenograft Model, Tissue Model and Cancer Model.

References related to locations published in J. Nutr.

PMID	Journal	Published Date	Author	Title
11823574	J. Nutr.	2002	DuPont MS et al.	Polyphenols from alcoholic apple cider are absorbed, metabolized and excreted by humans.
11925453	J. Nutr.	2002	Wolffram S et al.	Quercetin-3-glucoside is transported by the glucose carrier SGLT1 across the brush border membrane of rat small intestine.
12221254	J. Nutr.	2002	Arts IC et al.	Quercetin-3-glucoside is transported by the glucose carrier SGLT1 across the brush border membrane of rat small intestine.
12949368	J. Nutr.	2003	Cermak R et al.	The bioavailability of quercetin in pigs depends on the glycoside moiety and on dietary factors.
12612140	J. Nutr.	2003	Pal S et al.	Red wine polyphenolics increase LDL receptor expression and activity and suppress the secretion of ApoB100 from human HepG2 cells.
10801919	J. Nutr.	2000	Olthof MR et al.	Bioavailabilities of quercetin-3-glucoside and quercetin-4'-glucoside do not differ in humans.
11053503	J. Nutr.	2000	Walle T et al.	Quercetin glucosides are completely hydrolyzed in ileostomy patients before absorption.
21562239	J. Nutr.	2011	Cuevas MJ et al.	Suppression of amphiregulin/epidermal growth factor receptor signals contributes to the protective effects of quercetin in cirrhotic rats.
20032478	J. Nutr.	2010	Egert S et al.	Serum lipid and blood pressure responses to quercetin vary in overweight patients by apolipoprotein E genotype.
17951477	J. Nutr.	2007	Edwards RL et al.	Quercetin reduces blood pressure in hypertensive subjects.
17449583	J. Nutr.	2007	Ruiz PA et al.	Quercetin inhibits TNF-induced NF-kappaB transcription factor recruitment to proinflammatory gene promoters in murine intestinal epithelial cells.
17311951	J. Nutr.	2007	Carlstrom J et al.	A quercetin supplemented diet does not prevent cardiovascular complications in spontaneously hypertensive rats.
18424596	J. Nutr.	2008	Wiczkowski W et al.	Quercetin from shallots (Allium cepa L. var. aggregatum) is more bioavailable than its glucosides.
15735102	J. Nutr.	2005	Mertens-Talcott SU et al.	Ellagic acid potentiates the effect of quercetin on p21waf1/cip1, p53, and MAP-kinases without affecting intracellular generation of reactive oxygen species in vitro.
16365056	J. Nutr.	2006	Graf BA et al.	Rat gastrointestinal tissues metabolize quercetin.
15930438	J. Nutr.	2005	Martínez-Flórez S et al.	Quercetin attenuates nuclear factor-kappaB activation and nitric oxide production in interleukin-1beta-activated rat hepatocytes.
15987838	J. Nutr.	2005	Percival SS	Commentary on: tissue distribution of quercetin in rats and pigs.
15987855	J. Nutr.	2005	de Boer VC et al.	Tissue distribution of quercetin in rats and pigs.
17056790	J. Nutr.	2006	Granado-Serrano AB et al.	Quercetin induces apoptosis via caspase activation, regulation of Bcl-2, and inhibition of PI-3-kinase/Akt and ERK pathways in a human hepatoma cell line (HepG2).
17056814	J. Nutr.	2006	Dihal AA et al.	Quercetin, but not its glycosidated conjugate rutin, inhibits azoxymethane-induced colorectal carcinogenesis in F344 rats.
16614401	J. Nutr.	2006	Jackson SJ and Venema RC	Quercetin inhibits eNOS, microtubule polymerization, and mitotic progression in bovine aortic endothelial cells.
18492835	J. Nutr.	2008	Amasheh M et al.	Quercetin enhances epithelial barrier function and increases claudin-4 expression in Caco-2 cells.
22535755	J. Nutr.	2012	Panchal SK et al.	Quercetin ameliorates cardiovascular, hepatic, and metabolic changes in diet-induced metabolic syndrome in rats.
22915297	J. Nutr.	2012	Marcolin E et al.	Quercetin treatment ameliorates inflammation and fibrosis in mice with nonalcoholic steatohepatitis.
11053519	J. Nutr.	2000	Gee JM et al.	Intestinal transport of quercetin glycosides in rats involves both deglycosylation and interaction with the hexose transport pathway.