Wedelolactone

Wedelolactone is a lipid of Polyketides (PK) class. Wedelolactone is associated with abnormalities such as CLEFT LIP, CONGENITAL HEALED and Hepatitis. The involved functions are known as Signal Transduction, Cell Cycle Arrest, Apoptosis, luciferase activity and Metabolic Inhibition. Wedelolactone often locates in Protoplasm and Smooth muscle (tissue). The associated genes with Wedelolactone are CFB gene, Candidate Disease Gene, JAK2 gene, STAT2 gene and STAT3 gene.

References related to abnormalities published in J. Biol. Chem.


PMIDJournalPublished DateAuthorTitle
23580655J. Biol. Chem.2013Chen Z et al.Wedelolactone, a naturally occurring coumestan, enhances interferon-γ signaling through inhibiting STAT1 protein dephosphorylation.