D-cycloserine

D-cycloserine is a lipid of Polyketides (PK) class. D-cycloserine is associated with abnormalities such as Inflammatory disorder, Asthma, Rheumatoid Arthritis, Multiple Sclerosis and Inflammatory Bowel Diseases. The involved functions are known as Cellular Infiltration, Vascular Permeability, Stimulus, antagonists and Kinase Inhibitors [MoA]. D-cycloserine often locates in Tissue membrane, Body tissue, Protoplasm, Endothelium and Cell Wall. The associated genes with D-cycloserine are Genome, serine O-sulfate, Polypeptides, alpha-aminobutyric acid, (S)-isomer and Genes, Reporter. The related lipids are Sphingolipids, Fatty Acids, Sterols, 25-hydroxycholesterol and Fatty Acids, Unsaturated.

References related to abnormalities published in J. Biol. Chem.


PMIDJournalPublished DateAuthorTitle
12388538J. Biol. Chem.2002Erdreich-Epstein A et al.Ceramide signaling in fenretinide-induced endothelial cell apoptosis.
15302885J. Biol. Chem.2004Noda M et al.Self-protection mechanism in D-cycloserine-producing Streptomyces lavendulae. Gene cloning, characterization, and kinetics of its alanine racemase and D-alanyl-D-alanine ligase, which are target enzymes of D-cycloserine.
15302886J. Biol. Chem.2004Noda M et al.Structural evidence that alanine racemase from a D-cycloserine-producing microorganism exhibits resistance to its own product.