Retinal

Retinal is a lipid of Prenol Lipids (PR) class. Retinal is associated with abnormalities such as Retinal Detachment, Uveitis, Endophthalmitis, Infection and LEBER CONGENITAL AMAUROSIS, TYPE II (disorder). The involved functions are known as Pigment, immunoreactivity, Infiltration, Energy Absorption and chromophore. Retinal often locates in Entire visual system, Autosome, Membrane, Basement membrane and Thoracic region (surface region of back). The associated genes with Retinal are isorhodopsin, RPE65 gene, RND1 gene, RPE gene and CASP8AP2 gene. The related lipids are Phosphatidylserines, Membrane Lipids, Fatty Acids, Liposomes and oxidized lipid. The related experimental models are Mouse Model, Knock-out and Genetically Engineered Mouse.

References related to genes published in J. Biol. Chem.

PMID	Journal	Published Date	Author	Title
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22547062	J. Biol. Chem.	2012	Sexton TJ et al.	Melanopsin is highly resistant to light and chemical bleaching in vivo.
22570475	J. Biol. Chem.	2012	Boyer NP et al.	Lipofuscin and N-retinylidene-N-retinylethanolamine (A2E) accumulate in retinal pigment epithelium in absence of light exposure: their origin is 11-cis-retinal.
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22184108	J. Biol. Chem.	2012	Chen Y et al.	Mechanism of all-trans-retinal toxicity with implications for stargardt disease and age-related macular degeneration.
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24129572	J. Biol. Chem.	2013	Maeda T et al.	Retinal pigmented epithelial cells obtained from human induced pluripotent stem cells possess functional visual cycle enzymes in vitro and in vivo.
24403072	J. Biol. Chem.	2014	Yamashita T et al.	Evolution of mammalian Opn5 as a specialized UV-absorbing pigment by a single amino acid mutation.
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24106275	J. Biol. Chem.	2013	Opefi CA et al.	Retinitis pigmentosa mutants provide insight into the role of the N-terminal cap in rhodopsin folding, structure, and function.
26416885	J. Biol. Chem.	2015	Tsukamoto H et al.	Retinal Attachment Instability Is Diversified among Mammalian Melanopsins.
26391396	J. Biol. Chem.	2015	Sahu B et al.	Conditional Ablation of Retinol Dehydrogenase 10 in the Retinal Pigmented Epithelium Causes Delayed Dark Adaption in Mice.
25451936	J. Biol. Chem.	2015	Schafer CT and Farrens DL	Conformational selection and equilibrium governs the ability of retinals to bind opsin.