Retinal

Retinal is a lipid of Prenol Lipids (PR) class. Retinal is associated with abnormalities such as Retinal Detachment, Uveitis, Endophthalmitis, Infection and LEBER CONGENITAL AMAUROSIS, TYPE II (disorder). The involved functions are known as Pigment, immunoreactivity, Infiltration, Energy Absorption and chromophore. Retinal often locates in Entire visual system, Autosome, Membrane, Basement membrane and Thoracic region (surface region of back). The associated genes with Retinal are isorhodopsin, RPE65 gene, RND1 gene, RPE gene and CASP8AP2 gene. The related lipids are Phosphatidylserines, Membrane Lipids, Fatty Acids, Liposomes and oxidized lipid. The related experimental models are Mouse Model, Knock-out and Genetically Engineered Mouse.

References related to experimental models published in J. Biol. Chem.


PMIDJournalPublished DateAuthorTitle
11897783J. Biol. Chem.2002Van Hooser JP et al.Recovery of visual functions in a mouse model of Leber congenital amaurosis.
22074921J. Biol. Chem.2012Palczewski KChemistry and biology of vision.
23572532J. Biol. Chem.2013Kohno H et al.Photoreceptor proteins initiate microglial activation via Toll-like receptor 4 in retinal degeneration mediated by all-trans-retinal.
26391396J. Biol. Chem.2015Sahu B et al.Conditional Ablation of Retinol Dehydrogenase 10 in the Retinal Pigmented Epithelium Causes Delayed Dark Adaption in Mice.