N-acetylsphingosine

N-acetylsphingosine is a lipid of Sphingolipids (SP) class. N-acetylsphingosine is associated with abnormalities such as Morphologically altered structure, Atherosclerosis, Cardiovascular Diseases, Hyperinsulinism and Gigantism. The involved functions are known as inhibitors, anti-apoptosis, Apoptosis, Dephosphorylation and immunoreactivity. N-acetylsphingosine often locates in Plasma membrane, Mitochondria, Pore, Membrane and Cytoplasmic matrix. The associated genes with N-acetylsphingosine are EGR3 gene, CFB gene, FATE1 gene, P4HTM gene and PFDN4 gene. The related lipids are Sphingolipids, Cardiolipins, Glycerophospholipids, dihydroceramide and Phosphatidic Acid.

References related to genes published in J. Lipid Res.


PMIDJournalPublished DateAuthorTitle
11013311J. Lipid Res.2000Klapisz E et al.Sphingolipids and cholesterol modulate membrane susceptibility to cytosolic phospholipase A(2).
16990644J. Lipid Res.2006Ghering AB and Davidson WSCeramide structural features required to stimulate ABCA1-mediated cholesterol efflux to apolipoprotein A-I.
26116739J. Lipid Res.2015Ogiso H et al.Analysis of lipid-composition changes in plasma membrane microdomains.