phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

References related to functions published in Mol. Biol. Cell

PMID	Journal	Published Date	Author	Title
28035047	Mol. Biol. Cell	2017	Bone LN et al.	The acyltransferase LYCAT controls specific phosphoinositides and related membrane traffic.
28035045	Mol. Biol. Cell	2017	Levin R et al.	Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis.
27708138	Mol. Biol. Cell	2016	Xing M et al.	GOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edge.
25609085	Mol. Biol. Cell	2015	Malik S et al.	G protein βγ subunits regulate cardiomyocyte hypertrophy through a perinuclear Golgi phosphatidylinositol 4-phosphate hydrolysis pathway.
22553352	Mol. Biol. Cell	2012	Wood CS et al.	Local control of phosphatidylinositol 4-phosphate signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphatase.
18287542	Mol. Biol. Cell	2008	Demmel L et al.	The clathrin adaptor Gga2p is a phosphatidylinositol 4-phosphate effector at the Golgi exit.
18077555	Mol. Biol. Cell	2008	Balla A et al.	Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase IIIalpha.
17494868	Mol. Biol. Cell	2007	Wang J et al.	PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal.
10397762	Mol. Biol. Cell	1999	Rivas MP et al.	Pleiotropic alterations in lipid metabolism in yeast sac1 mutants: relationship to "bypass Sec14p" and inositol auxotrophy.