phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

References related to locations published in Mol. Biol. Cell

PMID	Journal	Published Date	Author	Title
28035045	Mol. Biol. Cell	2017	Levin R et al.	Multiphasic dynamics of phosphatidylinositol 4-phosphate during phagocytosis.
27798239	Mol. Biol. Cell	2016	Alli-Balogun GO et al.	Phosphatidylinositol 4-kinase IIβ negatively regulates invadopodia formation and suppresses an invasive cellular phenotype.
27708138	Mol. Biol. Cell	2016	Xing M et al.	GOLPH3 drives cell migration by promoting Golgi reorientation and directional trafficking to the leading edge.
26823017	Mol. Biol. Cell	2016	Henmi Y et al.	PtdIns4KIIα generates endosomal PtdIns(4)P and is required for receptor sorting at early endosomes.
26700316	Mol. Biol. Cell	2016	Stalder D and Novick PJ	The casein kinases Yck1p and Yck2p act in the secretory pathway, in part, by regulating the Rab exchange factor Sec2p.
25609085	Mol. Biol. Cell	2015	Malik S et al.	G protein βγ subunits regulate cardiomyocyte hypertrophy through a perinuclear Golgi phosphatidylinositol 4-phosphate hydrolysis pathway.
25165144	Mol. Biol. Cell	2014	Ling Y et al.	Osh4p is needed to reduce the level of phosphatidylinositol-4-phosphate on secretory vesicles as they mature.
22553352	Mol. Biol. Cell	2012	Wood CS et al.	Local control of phosphatidylinositol 4-phosphate signaling in the Golgi apparatus by Vps74 and Sac1 phosphoinositide phosphatase.
19369419	Mol. Biol. Cell	2009	Jović M et al.	Eps15 homology domain 1-associated tubules contain phosphatidylinositol-4-phosphate and phosphatidylinositol-(4,5)-bisphosphate and are required for efficient recycling.
18077555	Mol. Biol. Cell	2008	Balla A et al.	Maintenance of hormone-sensitive phosphoinositide pools in the plasma membrane requires phosphatidylinositol 4-kinase IIIalpha.
17494868	Mol. Biol. Cell	2007	Wang J et al.	PI4P promotes the recruitment of the GGA adaptor proteins to the trans-Golgi network and regulates their recognition of the ubiquitin sorting signal.
11514624	Mol. Biol. Cell	2001	Foti M et al.	Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology.