Epothilone B

Epothilone B is a lipid of Polyketides (PK) class. Epothilone b is associated with abnormalities such as Myelosuppression, Measurable Disease, Neuropathy, Neutropenia and Thrombocytopenia. The involved functions are known as Cell Cycle Arrest, Apoptosis, Signal Transduction, Cytokinesis and Caspase Activation. Epothilone b often locates in Mitochondria, Cytoplasmic matrix, Microtubules, Spindle and Protoplasm. The associated genes with Epothilone B are TNFSF10 gene, DIABLO gene, FADD gene, BCL2 gene and BCL2L1 gene. The related lipids are Promega and Phosphatidylserines. The related experimental models are Xenograft Model and Mouse Model.

References related to lipids published in Mol. Cancer Ther.


PMIDJournalPublished DateAuthorTitle
17308073Mol. Cancer Ther.2007Failly M et al.Combination of sublethal concentrations of epidermal growth factor receptor inhibitor and microtubule stabilizer induces apoptosis of glioblastoma cells.