Gossypol

Gossypol is a lipid of Prenol Lipids (PR) class. Gossypol is associated with abnormalities such as Paralytic Ileus, PARKINSON DISEASE, LATE-ONSET, Fibrillation, Hepatic necrosis and Lymphopenia. The involved functions are known as Atrophic, Ulcer, Necrosis, Apoptosis and antagonists. Gossypol often locates in Mucous Membrane, Epithelium, Blood, Microsomes, Liver and Autophagic vacuole. The associated genes with Gossypol are BCL2A1 gene, BCL2 gene, Transgenes, IGH@ gene cluster and Bax protein (53-86). The related lipids are Promega, proteoliposomes, Phosphatidylserines and Liposomes. The related experimental models are Transgenic Model and Xenograft Model.

References related to abnormalities published in Proc. Natl. Acad. Sci. U.S.A.

PMID	Journal	Published Date	Author	Title
10829068	Proc. Natl. Acad. Sci. U.S.A.	2000	Heiser V et al.	Inhibition of huntingtin fibrillogenesis by specific antibodies and small molecules: implications for Huntington's disease therapy.
20133848	Proc. Natl. Acad. Sci. U.S.A.	2010	Le A et al.	Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression.
17110445	Proc. Natl. Acad. Sci. U.S.A.	2006	Sunilkumar G et al.	Engineering cottonseed for use in human nutrition by tissue-specific reduction of toxic gossypol.