phosphatidylinositol-4-phosphate

phosphatidylinositol-4-phosphate is a lipid of Glycerophospholipids (GP) class. Phosphatidylinositol-4-phosphate is associated with abnormalities such as Renal tubular disorder, Oculocerebrorenal Syndrome, Lowe, Infection and Rhinovirus infection. The involved functions are known as Agent, Signal Transduction, Synthesis, Regulation and Process. Phosphatidylinositol-4-phosphate often locates in Membrane, Tissue membrane, Endosomes, Cytoskeleton and Cell membrane. The associated genes with phosphatidylinositol-4-phosphate are Homologous Gene, Homologous Protein, CDC42 gene, Genome and PIK4CB gene. The related lipids are phosphatidylinositol 4-phosphate, phosphatidylinositol 5-phosphate, Phosphatidylserines, phosphatidylinositol 3-phosphate and Total cholesterol.

References related to functions published in Proc. Natl. Acad. Sci. U.S.A.


PMIDJournalPublished DateAuthorTitle
27044099Proc. Natl. Acad. Sci. U.S.A.2016Sohn M et al.Lenz-Majewski mutations in PTDSS1 affect phosphatidylinositol 4-phosphate metabolism at ER-PM and ER-Golgi junctions.
26124136Proc. Natl. Acad. Sci. U.S.A.2015Ghugtyal V et al.Phosphatidylinositol-4-phosphate-dependent membrane traffic is critical for fungal filamentous growth.
25825728Proc. Natl. Acad. Sci. U.S.A.2015Jeschke A et al.Phosphatidylinositol 4-phosphate and phosphatidylinositol 3-phosphate regulate phagolysosome biogenesis.
17881569Proc. Natl. Acad. Sci. U.S.A.2007Fairn GD et al.The oxysterol binding protein Kes1p regulates Golgi apparatus phosphatidylinositol-4-phosphate function.