Epothilone D
Epothilone d is a lipid of Polyketides (PK) class. Epothilone d is associated with abnormalities such as Tauopathies, Neutropenia, Neuropathy and Hematological Disease. The involved functions are known as Mutation, Apoptosis, Mitotic arrest, Cell Growth and Anabolism. Epothilone d often locates in Cytoskeleton, Axon, Cell Wall, Chromosomes and Spindle. The associated genes with epothilone D are SLC33A1 gene, Chromatin, GTF2I gene and HEXA gene.
References related to functions published in Proc. Natl. Acad. Sci. U.S.A.
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 11562452 | Proc. Natl. Acad. Sci. U.S.A. | 2001 | Lichtner RB et al. | Subcellular distribution of epothilones in human tumor cells. |
| 23487739 | Proc. Natl. Acad. Sci. U.S.A. | 2013 | Xiong Y et al. | HDAC6 mutations rescue human tau-induced microtubule defects in Drosophila. |