Ecdysone

Ecdysone is a lipid of Sterol Lipids (ST) class. Ecdysone is associated with abnormalities such as Lafora Disease, Congenital Abnormality, Infection, protrusion and Morphologically altered structure. The involved functions are known as Cardiac Arrest, Transcription, Genetic, receptor function, Stimulus and Signal Transduction. Ecdysone often locates in Body tissue, Chromosomes, Polytene Chromosome, Epidermis and Muscle. The associated genes with Ecdysone are FATE1 gene, LGALS4 gene, Transgenes, LacZ Genes and C10orf27 gene. The related lipids are Steroids, FuGene, muristerone, N,N-dimethyl-N-hexadecyl-1-octadecylammonium chloride and 7-dehydrocholesterol. The related experimental models are Tissue Model.

References related to functions published in Proc. Natl. Acad. Sci. U.S.A.

PMID	Journal	Published Date	Author	Title
9342356	Proc. Natl. Acad. Sci. U.S.A.	1997	Carney GE et al.	DHR3, an ecdysone-inducible early-late gene encoding a Drosophila nuclear receptor, is required for embryogenesis.
9114033	Proc. Natl. Acad. Sci. U.S.A.	1997	Fletcher JC et al.	A steroid-triggered switch in E74 transcription factor isoforms regulates the timing of secondary-response gene expression.
9653129	Proc. Natl. Acad. Sci. U.S.A.	1998	Suhr ST et al.	High level transactivation by a modified Bombyx ecdysone receptor in mammalian cells without exogenous retinoid X receptor.
10200258	Proc. Natl. Acad. Sci. U.S.A.	1999	Dorstyn L et al.	DRONC, an ecdysone-inducible Drosophila caspase.
11687610	Proc. Natl. Acad. Sci. U.S.A.	2001	Stolarov J et al.	Design of a retroviral-mediated ecdysone-inducible system and its application to the expression profiling of the PTEN tumor suppressor.
10611292	Proc. Natl. Acad. Sci. U.S.A.	1999	Ahmed A et al.	Genomic structure and ecdysone regulation of the prophenoloxidase 1 gene in the malaria vector Anopheles gambiae.
10931948	Proc. Natl. Acad. Sci. U.S.A.	2000	Hock T et al.	The E23 early gene of Drosophila encodes an ecdysone-inducible ATP-binding cassette transporter capable of repressing ecdysone-mediated gene activation.
14762164	Proc. Natl. Acad. Sci. U.S.A.	2004	Gupta S et al.	Inducible, reversible, and stable RNA interference in mammalian cells.
19342482	Proc. Natl. Acad. Sci. U.S.A.	2009	Ishimoto H et al.	Ecdysone signaling regulates the formation of long-term courtship memory in adult Drosophila melanogaster.
17679695	Proc. Natl. Acad. Sci. U.S.A.	2007	Takemoto K et al.	Local initiation of caspase activation in Drosophila salivary gland programmed cell death in vivo.
16210248	Proc. Natl. Acad. Sci. U.S.A.	2005	Kuo CT et al.	Dendrite-specific remodeling of Drosophila sensory neurons requires matrix metalloproteases, ubiquitin-proteasome, and ecdysone signaling.
22393011	Proc. Natl. Acad. Sci. U.S.A.	2012	Veverytsa L and Allan DW	Temporally tuned neuronal differentiation supports the functional remodeling of a neuronal network in Drosophila.
23852731	Proc. Natl. Acad. Sci. U.S.A.	2013	Suzuki Y et al.	A molt timer is involved in the metamorphic molt in Manduca sexta larvae.
24799714	Proc. Natl. Acad. Sci. U.S.A.	2014	Rumpf S et al.	Drosophila Valosin-Containing Protein is required for dendrite pruning through a regulatory role in mRNA metabolism.
24778227	Proc. Natl. Acad. Sci. U.S.A.	2014	Mirth CK et al.	Juvenile hormone regulates body size and perturbs insulin signaling in Drosophila.
25605909	Proc. Natl. Acad. Sci. U.S.A.	2015	Ohhara Y et al.	Autocrine regulation of ecdysone synthesis by β3-octopamine receptor in the prothoracic gland is essential for Drosophila metamorphosis.