G(M3) Ganglioside

G(M3) Ganglioside is a lipid of Sphingolipids (SP) class. G(m3) ganglioside is associated with abnormalities such as Metabolic Diseases, Nodular glomerulosclerosis, Renal glomerular disease, Diabetes Mellitus and Hyperglycemia. The involved functions are known as Drug Interactions, Signal Transduction, Down-Regulation, Detergents and Ligand Binding. G(m3) ganglioside often locates in Tissue membrane, Body tissue, Cell surface, Membrane and Extracellular Matrix. The associated genes with G(M3) Ganglioside are PTPN11 gene, anti-IgM, Homologous Gene, SCAP2 gene and N-dodecyl-L-lysine amide. The related lipids are de-N-acetylneuraminyllactosylceramide, Membrane Lipids, Sphingolipids, stearic acid and sialogangliosides.

References related to functions published in Proc. Natl. Acad. Sci. U.S.A.

PMID	Journal	Published Date	Author	Title
22529395	Proc. Natl. Acad. Sci. U.S.A.	2012	Puryear WB et al.	HIV-1 incorporation of host-cell-derived glycosphingolipid GM3 allows for capture by mature dendritic cells.
11172001	Proc. Natl. Acad. Sci. U.S.A.	2001	Giraudo CG et al.	Physical and functional association of glycolipid N-acetyl-galactosaminyl and galactosyl transferases in the Golgi apparatus.
11171945	Proc. Natl. Acad. Sci. U.S.A.	2001	van Meer G	What sugar next? Dimerization of sphingolipid glycosyltransferases.
25902507	Proc. Natl. Acad. Sci. U.S.A.	2015	Randeria PS et al.	siRNA-based spherical nucleic acids reverse impaired wound healing in diabetic mice by ganglioside GM3 synthase knockdown.
21571640	Proc. Natl. Acad. Sci. U.S.A.	2011	Coskun Ü et al.	Regulation of human EGF receptor by lipids.
17699617	Proc. Natl. Acad. Sci. U.S.A.	2007	Kabayama K et al.	Dissociation of the insulin receptor and caveolin-1 complex by ganglioside GM3 in the state of insulin resistance.