Tetradecanoic acid

Tetradecanoic acid is a lipid of Fatty Acyls (FA) class. Tetradecanoic acid is associated with abnormalities such as Chronic lung disease, Infection, Spastic syndrome, Diabetes and Cardiovascular Diseases. The involved functions are known as Fatty acid biosynthetic process, Anabolism, lung alveolus development, 5-(carboxyamino)imidazole ribonucleotide mutase activity and Homeostasis. Tetradecanoic acid often locates in Structure of parenchyma of lung, Blood, Head, Membrane and Cytoplasmic matrix. The associated genes with Tetradecanoic acid are SLC33A1 gene, SFTPA1 gene, P4HTM gene, Polypeptides and GPR132 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, palmitoleic acid, Phosphatidylglycerols and Butanols.

References related to genes published in Proc. Natl. Acad. Sci. U.S.A.

PMID	Journal	Published Date	Author	Title
9789019	Proc. Natl. Acad. Sci. U.S.A.	1998	Gaffney BJ and Marsh D	High-frequency, spin-label EPR of nonaxial lipid ordering and motion in cholesterol-containing membranes.
14699046	Proc. Natl. Acad. Sci. U.S.A.	2004	Tang C et al.	Entropic switch regulates myristate exposure in the HIV-1 matrix protein.
14707265	Proc. Natl. Acad. Sci. U.S.A.	2004	Resh MD	A myristoyl switch regulates membrane binding of HIV-1 Gag.
21670298	Proc. Natl. Acad. Sci. U.S.A.	2011	Alioua A et al.	Unconventional myristoylation of large-conductance Ca²⁺-activated K⁺ channel (Slo1) via serine/threonine residues regulates channel surface expression.
16603631	Proc. Natl. Acad. Sci. U.S.A.	2006	Rowe DC et al.	The myristoylation of TRIF-related adaptor molecule is essential for Toll-like receptor 4 signal transduction.
23401539	Proc. Natl. Acad. Sci. U.S.A.	2013	Vlach J and Saad JS	Trio engagement via plasma membrane phospholipids and the myristoyl moiety governs HIV-1 matrix binding to bilayers.
25964330	Proc. Natl. Acad. Sci. U.S.A.	2015	Tsai SY et al.	Sigma-1 receptor regulates Tau phosphorylation and axon extension by shaping p35 turnover via myristic acid.