25-Hydroxycholesterol
25-Hydroxycholesterol is a lipid of Sterol Lipids (ST) class. 25-hydroxycholesterol is associated with abnormalities such as Hereditary Diseases, Atherosclerosis, Fatty Liver, Infection and Exanthema. The involved functions are known as Binding (Molecular Function), cholesterol binding, sterol binding, oxysterol binding and Regulation. 25-hydroxycholesterol often locates in Membrane, Golgi membrane, Cellular Membrane, Cytoplasmic matrix and Golgi Apparatus. The associated genes with 25-Hydroxycholesterol are PTPN7 gene, OSBP gene, N-glycylalanine, SCAP gene and TSPO gene. The related lipids are 25-hydroxycholesterol, Sterols, Hydroxycholesterols, 27-hydroxycholesterol and Steroids. The related experimental models are Knock-out.
References related to lipids published in Proc. Natl. Acad. Sci. U.S.A.
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 17428920 | Proc. Natl. Acad. Sci. U.S.A. | 2007 | Radhakrishnan A et al. | Sterol-regulated transport of SREBPs from endoplasmic reticulum to Golgi: oxysterols block transport by binding to Insig. |
| 24994901 | Proc. Natl. Acad. Sci. U.S.A. | 2014 | Gold ES et al. | 25-Hydroxycholesterol acts as an amplifier of inflammatory signaling. |
| 26023184 | Proc. Natl. Acad. Sci. U.S.A. | 2015 | Meffre D et al. | Liver X receptors alpha and beta promote myelination and remyelination in the cerebellum. |