Prostaglandin E2

Prostaglandin E2 is a lipid of Fatty Acyls (FA) class. Prostaglandin e2 is associated with abnormalities such as Renal glomerular disease, Arthritis, Degenerative polyarthritis, Pancreatitis and Rheumatoid Arthritis. The involved functions are known as enzyme pathway, Atherogenesis, Anabolism, inhibitors and Oxidants. Prostaglandin e2 often locates in Tissue membrane, Blood, Extracellular, Membrane and Protoplasm. The associated genes with Prostaglandin E2 are PTGS2 gene, TP53 gene, TNFRSF5 gene, FASTK Gene and TNF gene. The related lipids are Lipopolysaccharides, Steroids, monooxyethylene trimethylolpropane tristearate, Fatty Acids, Unsaturated and Promega. The related experimental models are Arthritis, Adjuvant-Induced, Xenograft Model, Experimental Autoimmune Encephalomyelitis, Cancer Model and Knock-out.

References related to functions published in Prostaglandins Other Lipid Mediat.


PMIDJournalPublished DateAuthorTitle
25263346Prostaglandins Other Lipid Mediat.2014Kassem KM et al.PGE2 reduces MMP-14 and increases plasminogen activator inhibitor-1 in cardiac fibroblasts.
16516814Prostaglandins Other Lipid Mediat.2006Matlhagela K and Taub MInvolvement of EP1 and EP2 receptors in the regulation of the Na,K-ATPase by prostaglandins in MDCK cells.
22120546Prostaglandins Other Lipid Mediat.2012Weems YS et al.In vivo intra-luteal implants of prostaglandin (PG) E1 or E2 (PGE1, PGE2) prevent luteolysis in cows. II: mRNA for PGF2α, EP1, EP2, EP3 (A-D), EP3A, EP3B, EP3C, EP3D, and EP4 prostanoid receptors in luteal tissue.
11060898Prostaglandins Other Lipid Mediat.2000Fain JN et al.Regulation of leptin release and lipolysis by PGE2 in rat adipose tissue.
28163121Prostaglandins Other Lipid Mediat.2017Kuroyanagi G et al.(-)-Epigallocatechin gallate synergistically potentiates prostaglandin E2-stimulated osteoprotegerin synthesis in osteoblasts.
28025036Prostaglandins Other Lipid Mediat.2017Aslan İ et al.Decreased eicosapentaenoic acid levels in acne vulgaris reveals the presence of a proinflammatory state.
27647508Prostaglandins Other Lipid Mediat.2016Konopka CK et al.Misoprostol modulates the gene expression prostaglandin E2 and oxidative stress markers in myometrial cells.
27174800Prostaglandins Other Lipid Mediat.2016Tamura K et al.A positive feedback loop between progesterone and microsomal prostaglandin E synthase-1-mediated PGE2 promotes production of both in mouse granulosa cells.
26711221Prostaglandins Other Lipid Mediat.2016Pruzanski W et al.Hydrolysis of lipoproteins by sPLA2's enhances mitogenesis and eicosanoid release from vascular smooth muscle cells: Diverse activity of sPLA2's IIA, V and X.
26692285Prostaglandins Other Lipid Mediat.2016Gose T et al.Prostaglandin transporter (OATP2A1/SLCO2A1) contributes to local disposition of eicosapentaenoic acid-derived PGE3.
26482178Prostaglandins Other Lipid Mediat.2015Kowalczyk-Zieba I et al.Lysophosphatidic acid modulates prostaglandin signalling in bovine steroidogenic luteal cells.
26463849Prostaglandins Other Lipid Mediat.2015Mawhin MA et al.The receptor EP3 to PGE2: A rational target to prevent atherothrombosis without inducing bleeding.
26209241Prostaglandins Other Lipid Mediat.2015Mastalerz L et al.Aspirin provocation increases 8-iso-PGE2 in exhaled breath condensate of aspirin-hypersensitive asthmatics.
26201058Prostaglandins Other Lipid Mediat.2015Yildirim FI et al.Aggravating effect of atorvastatin on indomethacin-induced gastric injury: Focus on PGE2, TNF-α, neutrophils and iNOS.
26150361Prostaglandins Other Lipid Mediat.2015Sasaki Y et al.Role of microsomal prostaglandin E synthase-1 (mPGES-1)-derived prostaglandin E2 in colon carcinogenesis.
26115647Prostaglandins Other Lipid Mediat.2015Gouveia-Figueira S and Nording MLValidation of a tandem mass spectrometry method using combined extraction of 37 oxylipins and 14 endocannabinoid-related compounds including prostamides from biological matrices.
26001880Prostaglandins Other Lipid Mediat.2015Le Maître E et al.Impaired vagus-mediated immunosuppression in microsomal prostaglandin E synthase-1 deficient mice.
25460828Prostaglandins Other Lipid Mediat.Montrose DC et al.The role of PGE2 in intestinal inflammation and tumorigenesis.
25460827Prostaglandins Other Lipid Mediat.Li YJ et al.Prostaglandin E2 switches from a stimulator to an inhibitor of cell migration after epithelial-to-mesenchymal transition.
23528231Prostaglandins Other Lipid Mediat.Leclerc P et al.Characterization of a new mPGES-1 inhibitor in rat models of inflammation.
23237743Prostaglandins Other Lipid Mediat.2013Xu J et al.Additive effect of prostaglandin E2 and adenosine in mouse experimental autoimmune encephalomyelitis.
23201570Prostaglandins Other Lipid Mediat.Li H et al.Regulation of T helper cell subsets by cyclooxygenases and their metabolites.
22178003Prostaglandins Other Lipid Mediat.2012Ells R et al.Sciadonic acid modulates prostaglandin E2 production by epithelial cells during infection with C. albicans and C. dubliniensis.
22101002Prostaglandins Other Lipid Mediat.2012Ferreri NR et al.Eicosanoids and tumor necrosis factor-alpha in the kidney.
21907301Prostaglandins Other Lipid Mediat.2011Chen EP and Smyth EMCOX-2 and PGE2-dependent immunomodulation in breast cancer.
21801847Prostaglandins Other Lipid Mediat.2011Swan CE and Breyer RMProstaglandin E2 modulation of blood pressure homeostasis: studies in rodent models.
20382255Prostaglandins Other Lipid Mediat.2010Shah NG et al.Prostaglandin E2 potentiates heat shock-induced heat shock protein 72 expression in A549 cells.
18406186Prostaglandins Other Lipid Mediat.2008Choudhary S et al.Effect of deletion of the prostaglandin EP2 receptor on the anabolic response to prostaglandin E2 and a selective EP2 receptor agonist.
17643883Prostaglandins Other Lipid Mediat.2007Antonucci R et al.Urinary prostaglandin E2 in the newborn and infant.
17164142Prostaglandins Other Lipid Mediat.2007Eisinger AL et al.The role of cyclooxygenase-2 and prostaglandins in colon cancer.
15287155Prostaglandins Other Lipid Mediat.2004Renò F et al.Exogenous prostaglandin E2 inhibits TPA induced matrix metalloproteinase-9 production in MCF-7 cells.
12428674Prostaglandins Other Lipid Mediat.2002Paris D et al.Pro-inflammatory effect of freshly solubilized beta-amyloid peptides in the brain.
11519793Prostaglandins Other Lipid Mediat.2001Konturek SJ et al.Implication of gastrin in cyclooxygenase-2 expression in Helicobacter pylori infected gastric ulceration.
10560620Prostaglandins Other Lipid Mediat.1999Hishinuma T et al.Microdetermination of prostaglandin E2 in joint fluid in rheumatoid arthritis patients using gas chromatography/selected ion monitoring.
10560612Prostaglandins Other Lipid Mediat.1999Lin WW et al.Modulation of inducible nitric oxide synthase induction by prostaglandin E2 in macrophages: distinct susceptibility in murine J774 and RAW 264.7 macrophages.