Prostaglandin E2

Prostaglandin E2 is a lipid of Fatty Acyls (FA) class. Prostaglandin e2 is associated with abnormalities such as Renal glomerular disease, Arthritis, Degenerative polyarthritis, Pancreatitis and Rheumatoid Arthritis. The involved functions are known as enzyme pathway, Atherogenesis, Anabolism, inhibitors and Oxidants. Prostaglandin e2 often locates in Tissue membrane, Blood, Extracellular, Membrane and Protoplasm. The associated genes with Prostaglandin E2 are PTGS2 gene, TP53 gene, TNFRSF5 gene, FASTK Gene and TNF gene. The related lipids are Lipopolysaccharides, Steroids, monooxyethylene trimethylolpropane tristearate, Fatty Acids, Unsaturated and Promega. The related experimental models are Arthritis, Adjuvant-Induced, Xenograft Model, Experimental Autoimmune Encephalomyelitis, Cancer Model and Knock-out.

References related to genes published in Prostaglandins Other Lipid Mediat.


PMIDJournalPublished DateAuthorTitle
25263346Prostaglandins Other Lipid Mediat.2014Kassem KM et al.PGE2 reduces MMP-14 and increases plasminogen activator inhibitor-1 in cardiac fibroblasts.
27174800Prostaglandins Other Lipid Mediat.2016Tamura K et al.A positive feedback loop between progesterone and microsomal prostaglandin E synthase-1-mediated PGE2 promotes production of both in mouse granulosa cells.
26692285Prostaglandins Other Lipid Mediat.2016Gose T et al.Prostaglandin transporter (OATP2A1/SLCO2A1) contributes to local disposition of eicosapentaenoic acid-derived PGE3.
26463849Prostaglandins Other Lipid Mediat.2015Mawhin MA et al.The receptor EP3 to PGE2: A rational target to prevent atherothrombosis without inducing bleeding.
25460827Prostaglandins Other Lipid Mediat.Li YJ et al.Prostaglandin E2 switches from a stimulator to an inhibitor of cell migration after epithelial-to-mesenchymal transition.
23528231Prostaglandins Other Lipid Mediat.Leclerc P et al.Characterization of a new mPGES-1 inhibitor in rat models of inflammation.
23201570Prostaglandins Other Lipid Mediat.Li H et al.Regulation of T helper cell subsets by cyclooxygenases and their metabolites.
22178003Prostaglandins Other Lipid Mediat.2012Ells R et al.Sciadonic acid modulates prostaglandin E2 production by epithelial cells during infection with C. albicans and C. dubliniensis.
21907301Prostaglandins Other Lipid Mediat.2011Chen EP and Smyth EMCOX-2 and PGE2-dependent immunomodulation in breast cancer.
20382255Prostaglandins Other Lipid Mediat.2010Shah NG et al.Prostaglandin E2 potentiates heat shock-induced heat shock protein 72 expression in A549 cells.
17164142Prostaglandins Other Lipid Mediat.2007Eisinger AL et al.The role of cyclooxygenase-2 and prostaglandins in colon cancer.
15287155Prostaglandins Other Lipid Mediat.2004Renò F et al.Exogenous prostaglandin E2 inhibits TPA induced matrix metalloproteinase-9 production in MCF-7 cells.
10560620Prostaglandins Other Lipid Mediat.1999Hishinuma T et al.Microdetermination of prostaglandin E2 in joint fluid in rheumatoid arthritis patients using gas chromatography/selected ion monitoring.