Lycopene

Lycopene is a lipid of Prenol Lipids (PR) class. Lycopene is associated with abnormalities such as Consumption-archaic term for TB, Chronic disease, Dehydration, furuncle and Cardiovascular Diseases. The involved functions are known as Cell Differentiation process, Signal Transduction, Biochemical Pathway, Mutation and IGF-1 Signaling Pathway. Lycopene often locates in Body tissue, Hepatic, Blood, Adipose tissue and Structure of parenchyma of lung. The associated genes with Lycopene are EPB41L2 gene, VEGFB gene, P4HTM gene, FATE1 gene and SLC33A1 gene. The related lipids are Micelles, Liposomes, Total cholesterol, Steroids and apo-10'-lycopenoic acid. The related experimental models are Mouse Model, Knock-out, Cancer Model, Transgenic Model and Xenograft Model.

References related to genes published in Others

PMID	Journal	Published Date	Author	Title
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20178989	J. Biol. Chem.	2010	Yu Q et al.	The lycopene cyclase CrtY from Pantoea ananatis (formerly Erwinia uredovora) catalyzes an FADred-dependent non-redox reaction.
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17606904	Proc. Natl. Acad. Sci. U.S.A.	2007	Maresca JA et al.	Identification of a fourth family of lycopene cyclases in photosynthetic bacteria.
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22158914	Eur J Public Health	2012	Karppi J et al.	Low serum lycopene and β-carotene increase risk of acute myocardial infarction in men.
22865070	Appl. Environ. Microbiol.	2012	Wang GS et al.	High-level production of the industrial product lycopene by the photosynthetic bacterium Rhodospirillum rubrum.
23386264	Plant Cell	2013	Fujisawa M et al.	A large-scale identification of direct targets of the tomato MADS box transcription factor RIPENING INHIBITOR reveals the regulation of fruit ripening.
23076979	Eur J Cardiovasc Nurs	2013	Biddle M et al.	Higher dietary lycopene intake is associated with longer cardiac event-free survival in patients with heart failure.
24085778	Cancer Prev Res (Phila)	2013	Ip BC et al.	Lycopene metabolite, apo-10'-lycopenoic acid, inhibits diethylnitrosamine-initiated, high fat diet-promoted hepatic inflammation and tumorigenesis in mice.
23483004	Cancer Prev Res (Phila)	2013	Qiu X et al.	Effects of lycopene on protein expression in human primary prostatic epithelial cells.
24375130	Appl. Environ. Microbiol.	2014	Matthäus F et al.	Production of lycopene in the non-carotenoid-producing yeast Yarrowia lipolytica.
24463248	J. Natl. Cancer Inst.	2014	Zu K et al.	Dietary lycopene, angiogenesis, and prostate cancer: a prospective study in the prostate-specific antigen era.
27406826	Mol. Cancer Res.	2016	Gong X et al.	Mitochondrial β-Carotene 9',10' Oxygenase Modulates Prostate Cancer Growth via NF-κB Inhibition: A Lycopene-Independent Function.
26141149	Metab. Eng.	2015	Watstein DM et al.	Precise metabolic engineering of carotenoid biosynthesis in Escherichia coli towards a low-cost biosensor.
25712483	J. Bacteriol.	2015	Yang Y et al.	Complete biosynthetic pathway of the C50 carotenoid bacterioruberin from lycopene in the extremely halophilic archaeon Haloarcula japonica.
25602702	Arch. Biochem. Biophys.	2015	Sahin K et al.	Lycopene in the prevention of renal cell cancer in the TSC2 mutant Eker rat model.
25592162	Arch. Biochem. Biophys.	2015	Stice CP et al.	Dietary tomato powder inhibits alcohol-induced hepatic injury by suppressing cytochrome p450 2E1 induction in rodent models.
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25315431	Cancer Prev Res (Phila)	2014	Wan L et al.	Dietary tomato and lycopene impact androgen signaling- and carcinogenesis-related gene expression during early TRAMP prostate carcinogenesis.
25293877	Cancer Prev Res (Phila)	2014	Ip BC et al.	Lycopene attenuated hepatic tumorigenesis via differential mechanisms depending on carotenoid cleavage enzyme in mice.