Lycopene is a lipid of Prenol Lipids (PR) class. Lycopene is associated with abnormalities such as Consumption-archaic term for TB, Chronic disease, Dehydration, furuncle and Cardiovascular Diseases. The involved functions are known as Cell Differentiation process, Signal Transduction, Biochemical Pathway, Mutation and IGF-1 Signaling Pathway. Lycopene often locates in Body tissue, Hepatic, Blood, Adipose tissue and Structure of parenchyma of lung. The associated genes with Lycopene are EPB41L2 gene, VEGFB gene, P4HTM gene, FATE1 gene and SLC33A1 gene. The related lipids are Micelles, Liposomes, Total cholesterol, Steroids and apo-10'-lycopenoic acid. The related experimental models are Mouse Model, Knock-out, Cancer Model, Transgenic Model and Xenograft Model.
PMID | Journal | Published Date | Author | Title |
---|---|---|---|---|
9546156 | Appl. Environ. Microbiol. | 1998 | Miura Y et al. | Production of the carotenoids lycopene, beta-carotene, and astaxanthin in the food yeast Candida utilis. |
9521160 | J. Natl. Cancer Inst. | 1998 | Olson KB and Pienta KJ | Vitamins A and E: further clues for prostate cancer prevention. |
10050865 | J. Natl. Cancer Inst. | 1999 | Giovannucci E | Tomatoes, tomato-based products, lycopene, and cancer: review of the epidemiologic literature. |
10096552 | Cancer Res. | 1999 | Gann PH et al. | Lower prostate cancer risk in men with elevated plasma lycopene levels: results of a prospective analysis. |
10438533 | J. Biol. Chem. | 1999 | Deshpande A and Sonar S | Bacterioopsin-triggered retinal biosynthesis is inhibited by bacteriorhodopsin formation in Halobacterium salinarium. |
11489752 | Cancer Epidemiol. Biomarkers Prev. | 2001 | Kucuk O et al. | Phase II randomized clinical trial of lycopene supplementation before radical prostatectomy. |
11752012 | J. Natl. Cancer Inst. | 2001 | Chen L et al. | Oxidative DNA damage in prostate cancer patients consuming tomato sauce-based entrees as a whole-food intervention. |
11744518 | Am. J. Epidemiol. | 2001 | Kabagambe EK et al. | Application of the method of triads to evaluate the performance of food frequency questionnaires and biomarkers as indicators of long-term dietary intake. |
12034581 | Am. J. Epidemiol. | 2002 | Vogt TM et al. | Serum lycopene, other serum carotenoids, and risk of prostate cancer in US Blacks and Whites. |
12810641 | Cancer Res. | 2003 | Liu C et al. | Lycopene supplementation inhibits lung squamous metaplasia and induces apoptosis via up-regulating insulin-like growth factor-binding protein 3 in cigarette smoke-exposed ferrets. |
12736146 | Am. J. Physiol. Gastrointest. Liver Physiol. | 2003 | Tyssandier V et al. | Processing of vegetable-borne carotenoids in the human stomach and duodenum. |
12463216 | Plant Physiol. | 2002 | Minorsky PV | Lycopene and human health. |
12867539 | J. Lipid Res. | 2003 | Diwadkar-Navsariwala V et al. | A physiological pharmacokinetic model describing the disposition of lycopene in healthy men. |
10634784 | Science | 2000 | Ye X et al. | Engineering the provitamin A (beta-carotene) biosynthetic pathway into (carotenoid-free) rice endosperm. |
11022591 | CMAJ | 2000 | Agarwal S and Rao AV | Tomato lycopene and its role in human health and chronic diseases. |
14600081 | J. Natl. Cancer Inst. | 2003 | Gann PH and Khachik F | Tomatoes or lycopene versus prostate cancer: is evolution anti-reductionist? |
14600090 | J. Natl. Cancer Inst. | 2003 | Boileau TW et al. | Prostate carcinogenesis in N-methyl-N-nitrosourea (NMU)-testosterone-treated rats fed tomato powder, lycopene, or energy-restricted diets. |
15159319 | Cancer Epidemiol. Biomarkers Prev. | 2004 | Gustin DM et al. | Single-dose pharmacokinetic study of lycopene delivered in a well-defined food-based lycopene delivery system (tomato paste-oil mixture) in healthy adult male subjects. |
19364801 | CMAJ | 2009 | Shaw JA and Koti M | Clinical images. |
19587100 | Plant Physiol. | 2009 | Apel W and Bock R | Enhancement of carotenoid biosynthesis in transplastomic tomatoes by induced lycopene-to-provitamin A conversion. |
20348305 | Appl. Environ. Microbiol. | 2010 | Choi HS et al. | In silico identification of gene amplification targets for improvement of lycopene production. |
20178989 | J. Biol. Chem. | 2010 | Yu Q et al. | The lycopene cyclase CrtY from Pantoea ananatis (formerly Erwinia uredovora) catalyzes an FADred-dependent non-redox reaction. |
17911344 | Am. J. Physiol. Endocrinol. Metab. | 2007 | Napolitano M et al. | Effects of lycopene on the induction of foam cell formation by modified LDL. |
17606904 | Proc. Natl. Acad. Sci. U.S.A. | 2007 | Maresca JA et al. | Identification of a fourth family of lycopene cyclases in photosynthetic bacteria. |
15657364 | Mol. Cancer Ther. | 2005 | Ben-Dor A et al. | Carotenoids activate the antioxidant response element transcription system. |
15894655 | Cancer Epidemiol. Biomarkers Prev. | 2005 | Sesso HD et al. | Dietary and plasma lycopene and the risk of breast cancer. |
16434593 | Cancer Epidemiol. Biomarkers Prev. | 2006 | Kirsh VA et al. | A prospective study of lycopene and tomato product intake and risk of prostate cancer. |
17121935 | Mol. Cancer Ther. | 2006 | Liu A et al. | Absorption and subcellular localization of lycopene in human prostate cancer cells. |
17085635 | Eukaryotic Cell | 2007 | Cunningham FX et al. | Carotenoid biosynthesis in the primitive red alga Cyanidioschyzon merolae. |
16621828 | J. Bacteriol. | 2006 | Mohamed HE and Vermaas WF | Sll0254 (CrtL(diox)) is a bifunctional lycopene cyclase/dioxygenase in cyanobacteria producing myxoxanthophyll. |
21430075 | Cancer Prev Res (Phila) | 2011 | van Breemen RB et al. | Antioxidant effects of lycopene in African American men with prostate cancer or benign prostate hyperplasia: a randomized, controlled trial. |
22865070 | Appl. Environ. Microbiol. | 2012 | Wang GS et al. | High-level production of the industrial product lycopene by the photosynthetic bacterium Rhodospirillum rubrum. |
23749762 | Reprod Sci | 2014 | Raj MV et al. | Impact of lycopene on epididymal androgen and estrogen receptors' expression in polychlorinated biphenyls-exposed rat. |
23483004 | Cancer Prev Res (Phila) | 2013 | Qiu X et al. | Effects of lycopene on protein expression in human primary prostatic epithelial cells. |
24375130 | Appl. Environ. Microbiol. | 2014 | Matthäus F et al. | Production of lycopene in the non-carotenoid-producing yeast Yarrowia lipolytica. |
27406826 | Mol. Cancer Res. | 2016 | Gong X et al. | Mitochondrial β-Carotene 9',10' Oxygenase Modulates Prostate Cancer Growth via NF-κB Inhibition: A Lycopene-Independent Function. |
25602702 | Arch. Biochem. Biophys. | 2015 | Sahin K et al. | Lycopene in the prevention of renal cell cancer in the TSC2 mutant Eker rat model. |
25592162 | Arch. Biochem. Biophys. | 2015 | Stice CP et al. | Dietary tomato powder inhibits alcohol-induced hepatic injury by suppressing cytochrome p450 2E1 induction in rodent models. |
25469376 | Adv Nutr | 2014 | Burton-Freeman B and Sesso HD | Whole food versus supplement: comparing the clinical evidence of tomato intake and lycopene supplementation on cardiovascular risk factors. |
25315431 | Cancer Prev Res (Phila) | 2014 | Wan L et al. | Dietary tomato and lycopene impact androgen signaling- and carcinogenesis-related gene expression during early TRAMP prostate carcinogenesis. |
25293877 | Cancer Prev Res (Phila) | 2014 | Ip BC et al. | Lycopene attenuated hepatic tumorigenesis via differential mechanisms depending on carotenoid cleavage enzyme in mice. |