AFBI

AFBI is a lipid of Polyketides (PK) class. Afbi is associated with abnormalities such as Pyotraumatic dermatitis, Infection, Hepatitis, Liver diseases and Hepatitis B. The involved functions are known as Immune response, Mutation, Anabolism, Metabolic Inhibition and Increased Sensitivy. Afbi often locates in Body tissue, Hepatic, Cytoplasm, Blood and Micronucleus. The associated genes with AFBI are TP53 gene, Genome, Transgenes, FATE1 gene and MANEA gene. The related lipids are Lipopolysaccharides, Lipid Peroxides, 1-(2-cyano-3,12-dioxooleana-1,9-dien-28-oyl) imidazole and Liposomes.

References related to abnormalities published in Others


PMIDJournalPublished DateAuthorTitle
12388740J. Virol.2002Madden CR et al.Altered DNA mutation spectrum in aflatoxin b1-treated transgenic mice that express the hepatitis B virus x protein.
19850960Gut2010Fox JG et al.Gut microbes define liver cancer risk in mice exposed to chemical and viral transgenic hepatocarcinogens.
17978082Am. J. Trop. Med. Hyg.2007Chen CH et al.Aflatoxin exposure and hepatitis C virus in advanced liver disease in a hepatitis C virus endemic area in Taiwan.
17965344J. Med. Microbiol.2007Murugavel KG et al.Prevalence of aflatoxin B1 in liver biopsies of proven hepatocellular carcinoma in India determined by an in-house immunoperoxidase test.
18299423Reproduction2008Faisal K et al.Spermatotoxic effect of aflatoxin B1 in rat: extrusion of outer dense fibres and associated axonemal microtubule doublets of sperm flagellum.
15944194Int. Immunol.2005Jiang Y et al.Aflatoxin B1 albumin adduct levels and cellular immune status in Ghanaians.
26677209Cancer Epidemiol. Biomarkers Prev.2016Huang XY et al.Polymorphisms of a Disintegrin and Metalloproteinase with Thrombospondin Motifs 5 and Aflatoxin B1-Related Hepatocellular Carcinoma.
26035378Dis Model Mech2015Teoh WW et al.Molecular characterization of hepatocarcinogenesis using mouse models.
25450479Toxicol. Appl. Pharmacol.2015Techapiesancharoenkij N et al.Sulforaphane, a cancer chemopreventive agent, induces pathways associated with membrane biosynthesis in response to tissue damage by aflatoxin B1.
24662598Cancer Prev Res (Phila)2014Johnson NM et al.Complete protection against aflatoxin B(1)-induced liver cancer with a triterpenoid: DNA adduct dosimetry, molecular signature, and genotoxicity threshold.