phylloquinone

Phylloquinone is a lipid of Prenol Lipids (PR) class. Phylloquinone is associated with abnormalities such as Vitamin K Deficiency, Malnutrition, Consumption-archaic term for TB, Osteoporosis and Hyperostosis, Diffuse Idiopathic Skeletal. The involved functions are known as Ingestion, Blood Circulation, Genetic Polymorphism, Intestinal Absorption and Process. Phylloquinone often locates in Blood, Body tissue, Hepatic, Membrane and Entire bony skeleton. The associated genes with phylloquinone are Vitamin K Epoxide Reductase Complex, Subunit 1, GGCX gene, CYP4F2 gene, Alleles and APOE gene. The related lipids are Micelles, 208-G, Fatty Acids, Total cholesterol and Sphingolipids. The related experimental models are Knock-out.

References related to abnormalities published in Others


PMIDJournalPublished DateAuthorTitle
10722690J. Biol. Chem.2000Johnson TW et al.Recruitment of a foreign quinone into the A(1) site of photosystem I. I. Genetic and physiological characterization of phylloquinone biosynthetic pathway mutants in Synechocystis sp. pcc 6803.
19321747Proc. Natl. Acad. Sci. U.S.A.2009Widhalm JR et al.A dedicated thioesterase of the Hotdog-fold family is required for the biosynthesis of the naphthoquinone ring of vitamin K1.
19675304Am. J. Physiol., Cell Physiol.2009Atkins GJ et al.Vitamin K promotes mineralization, osteoblast-to-osteocyte transition, and an anticatabolic phenotype by {gamma}-carboxylation-dependent and -independent mechanisms.
20167683Clin J Am Soc Nephrol2010Holden RM et al.Vitamins K and D status in stages 3-5 chronic kidney disease.
17712007Clin. Chem.2007Azharuddin MK et al.HPLC method for plasma vitamin K1: effect of plasma triglyceride and acute-phase response on circulating concentrations.
18625626Ann. Rheum. Dis.2008Neogi T et al.Vitamin K in hand osteoarthritis: results from a randomised clinical trial.
24929459J Acupunct Meridian Stud2014Chao MT et al.Increase in plasma phylloquinone concentrations following acupoint injection for the treatment of primary dysmenorrhea.