Ecdysone
Ecdysone is a lipid of Sterol Lipids (ST) class. Ecdysone is associated with abnormalities such as Lafora Disease, Congenital Abnormality, Infection, protrusion and Morphologically altered structure. The involved functions are known as Cardiac Arrest, Transcription, Genetic, receptor function, Stimulus and Signal Transduction. Ecdysone often locates in Body tissue, Chromosomes, Polytene Chromosome, Epidermis and Muscle. The associated genes with Ecdysone are FATE1 gene, LGALS4 gene, Transgenes, LacZ Genes and C10orf27 gene. The related lipids are Steroids, FuGene, muristerone, N,N-dimethyl-N-hexadecyl-1-octadecylammonium chloride and 7-dehydrocholesterol. The related experimental models are Tissue Model.
References related to abnormalities published in Others
| PMID | Journal | Published Date | Author | Title |
|---|---|---|---|---|
| 11152752 | Physiol. Rev. | 2001 | Mazzanti M et al. | Electrical dimension of the nuclear envelope. |
| 11514618 | Mol. Biol. Cell | 2001 | Kondylis V et al. | Biogenesis of Golgi stacks in imaginal discs of Drosophila melanogaster. |
| 11687610 | Proc. Natl. Acad. Sci. U.S.A. | 2001 | Stolarov J et al. | Design of a retroviral-mediated ecdysone-inducible system and its application to the expression profiling of the PTEN tumor suppressor. |
| 12958367 | Science | 2003 | Kozlova T and Thummel CS | Essential roles for ecdysone signaling during Drosophila mid-embryonic development. |
| 12736135 | Am. J. Physiol., Cell Physiol. | 2003 | Lai JF et al. | An ecdysone and tetracycline dual regulatory expression system for studies on Rac1 small GTPase-mediated signaling. |
| 11102372 | Genetics | 2000 | Gates J and Thummel CS | An enhancer trap screen for ecdysone-inducible genes required for Drosophila adult leg morphogenesis. |
| 10931948 | Proc. Natl. Acad. Sci. U.S.A. | 2000 | Hock T et al. | The E23 early gene of Drosophila encodes an ecdysone-inducible ATP-binding cassette transporter capable of repressing ecdysone-mediated gene activation. |
| 14668390 | Genetics | 2003 | Ward RE et al. | Genetic modifier screens in Drosophila demonstrate a role for Rho1 signaling in ecdysone-triggered imaginal disc morphogenesis. |
| 17761811 | Genes Dev. | 2007 | Varghese J and Cohen SM | microRNA miR-14 acts to modulate a positive autoregulatory loop controlling steroid hormone signaling in Drosophila. |
| 21715559 | Genes Dev. | 2011 | Cáceres L et al. | Nitric oxide coordinates metabolism, growth, and development via the nuclear receptor E75. |
| 23652443 | EMBO J. | 2013 | Rus F et al. | Ecdysone triggered PGRP-LC expression controls Drosophila innate immunity. |
| 24374353 | Genetics | 2014 | Ihry RJ and Bashirullah A | Genetic control of specificity to steroid-triggered responses in Drosophila. |
| 21423150 | EMBO J. | 2011 | König A et al. | Ecdysteroids affect Drosophila ovarian stem cell niche formation and early germline differentiation. |
| 12963111 | Mech. Dev. | 2003 | Schubiger M et al. | Isoform specific control of gene activity in vivo by the Drosophila ecdysone receptor. |
| 20810883 | J. Neurosci. | 2010 | Liu Z et al. | Distinct presynaptic and postsynaptic dismantling processes of Drosophila neuromuscular junctions during metamorphosis. |
| 20688956 | Blood | 2010 | Sinenko SA et al. | Genetic manipulation of AML1-ETO-induced expansion of hematopoietic precursors in a Drosophila model. |
| 18554690 | Acta Histochem. | 2009 | Goncu E and Parlak O | Morphological changes and patterns of ecdysone receptor B1 immunolocalization in the anterior silk gland undergoing programmed cell death in the silkworm, Bombyx mori. |
| 18061567 | Dev. Cell | 2007 | McBrayer Z et al. | Prothoracicotropic hormone regulates developmental timing and body size in Drosophila. |
| 16264191 | Genes Dev. | 2005 | Badenhorst P et al. | The Drosophila nucleosome remodeling factor NURF is required for Ecdysteroid signaling and metamorphosis. |
| 11703937 | Dev. Cell | 2001 | Thummel CS | Molecular mechanisms of developmental timing in C. elegans and Drosophila. |
| 26773159 | J. Immunol. | 2016 | Sun W et al. | Ecdysone Titer Determined by 3DE-3β-Reductase Enhances the Immune Response in the Silkworm. |
| 26715667 | Genetics | 2016 | Mendes CC and Mirth CK | Stage-Specific Plasticity in Ovary Size Is Regulated by Insulin/Insulin-Like Growth Factor and Ecdysone Signaling in Drosophila. |
| 25605909 | Proc. Natl. Acad. Sci. U.S.A. | 2015 | Ohhara Y et al. | Autocrine regulation of ecdysone synthesis by β3-octopamine receptor in the prothoracic gland is essential for Drosophila metamorphosis. |
| 25126791 | Cell | 2014 | Homem CCF et al. | Ecdysone and mediator change energy metabolism to terminate proliferation in Drosophila neural stem cells. |