Tetradecanoic acid

Tetradecanoic acid is a lipid of Fatty Acyls (FA) class. Tetradecanoic acid is associated with abnormalities such as Chronic lung disease, Infection, Spastic syndrome, Diabetes and Cardiovascular Diseases. The involved functions are known as Fatty acid biosynthetic process, Anabolism, lung alveolus development, 5-(carboxyamino)imidazole ribonucleotide mutase activity and Homeostasis. Tetradecanoic acid often locates in Structure of parenchyma of lung, Blood, Head, Membrane and Cytoplasmic matrix. The associated genes with Tetradecanoic acid are SLC33A1 gene, SFTPA1 gene, P4HTM gene, Polypeptides and GPR132 gene. The related lipids are Fatty Acids, Nonesterified Fatty Acids, palmitoleic acid, Phosphatidylglycerols and Butanols.

References related to abnormalities published in Others

PMID	Journal	Published Date	Author	Title
9103475	J. Pharmacol. Exp. Ther.	1997	Naze S et al.	Activation of phospholipase D by endothelin-1 in rat myometrium. Role of calcium and protein kinase C.
9611229	Nucleic Acids Res.	1998	Cok SJ et al.	Transcription of INO2 and INO4 is regulated by the state of protein N-myristoylation in Saccharomyces cerevisiae.
11238766	J. Nutr.	2001	Wolk A et al.	Fatty acid composition of adipose tissue and serum lipids are valid biological markers of dairy fat intake in men.
12118067	J. Cell. Sci.	2002	Navarro-Lérida I et al.	Distance-dependent cellular palmitoylation of de-novo-designed sequences and their translocation to plasma membrane subdomains.
12185287	J. Gen. Virol.	2002	Mannová P et al.	Analysis of mouse polyomavirus mutants with lesions in the minor capsid proteins.
21636561	J. Appl. Physiol.	2011	Bernhard W et al.	Increased palmitoyl-myristoyl-phosphatidylcholine in neonatal rat surfactant is lung specific and correlates with oral myristic acid supply.
19955401	Am. J. Clin. Nutr.	2010	Bradbury KE et al.	The serum fatty acids myristic acid and linoleic acid are better predictors of serum cholesterol concentrations when measured as molecular percentages rather than as absolute concentrations.
17977947	Am. J. Physiol., Cell Physiol.	2008	White J et al.	Diabetic HDL-associated myristic acid inhibits acetylcholine-induced nitric oxide generation by preventing the association of endothelial nitric oxide synthase with calmodulin.
17616681	Cancer Res.	2007	Adam RM et al.	Cholesterol sensitivity of endogenous and myristoylated Akt.
16988223	Infect. Immun.	2006	Debierre-Grockiego F et al.	Fatty acids from Plasmodium falciparum down-regulate the toxic activity of malaria glycosylphosphatidylinositols.
22391103	Mol. Pharmacol.	2012	Puhl AC et al.	Mode of peroxisome proliferator-activated receptor γ activation by luteolin.
19357638	Mol. Syst. Biol.	2009	Atherton HJ et al.	Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse.
21382489	Biochim. Biophys. Acta	2011	Varga T et al.	PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation.
20805277	Diabetes Care	2010	Chen X et al.	Differences in maternal circulating fatty acid composition and dietary fat intake in women with gestational diabetes mellitus or mild gestational hyperglycemia.
20713404	Philos. Trans. R. Soc. Lond., B, Biol. Sci.	2010	Hawkesworth S et al.	Feeding the world healthily: the challenge of measuring the effects of agriculture on health.
20045147	Metab. Clin. Exp.	2010	Lemaitre RN et al.	Endogenous red blood cell membrane fatty acids and sudden cardiac arrest.
19934003	Diabetes	2010	Yeop Han C et al.	Differential effect of saturated and unsaturated free fatty acids on the generation of monocyte adhesion and chemotactic factors by adipocytes: dissociation of adipocyte hypertrophy from inflammation.
18068687	Biochem. Pharmacol.	2008	Isenberg JS et al.	Differential effects of ABT-510 and a CD36-binding peptide derived from the type 1 repeats of thrombospondin-1 on fatty acid uptake, nitric oxide signaling, and caspase activation in vascular cells.
18025213	J. Immunol.	2007	Asai Y et al.	Soluble CD14 discriminates slight structural differences between lipid as that lead to distinct host cell activation.
15637134	Clin. Chem.	2005	Fernández-Real JM et al.	Circulating adiponectin and plasma fatty acid profile.
14724220	J. Pharmacol. Exp. Ther.	2004	French KJ et al.	Cyclohexyl-octahydro-pyrrolo[1,2-a]pyrazine-based inhibitors of human N-myristoyltransferase-1.
27237364	Cell Host Microbe	2016	Trindade S et al.	Trypanosoma brucei Parasites Occupy and Functionally Adapt to the Adipose Tissue in Mice.
25833975	Am. J. Clin. Nutr.	2015	Drehmer M et al.	Associations of dairy intake with glycemia and insulinemia, independent of obesity, in Brazilian adults: the Brazilian Longitudinal Study of Adult Health (ELSA-Brasil).
25773595	Mol. Cell	2015	Burnaevskiy N et al.	Myristoylome profiling reveals a concerted mechanism of ARF GTPase deacylation by the bacterial protease IpaJ.