Cholic acid

Cholic acid is a lipid of Sterol Lipids (ST) class. Cholic acid is associated with abnormalities such as Cholestasis, Intrahepatic Cholestasis, Atherosclerosis, Diabetes and cholesterol gallstones. The involved functions are known as Homeostasis, Enterohepatic Circulation, Proliferation (morphologic abnormality), Process and Cell Proliferation. Cholic acid often locates in Hepatic, Cytoplasmic matrix, Membrane, Protoplasm and Tissue membrane. The associated genes with Cholic acid are CYP27A1 gene, ABCB11 gene, NR5A2 gene, SLC10A2 gene and SLC10A1 gene. The related lipids are ursocholic acid, Steroids, Cholestenes, Cholestanes and cholanic acid.

References related to abnormalities published in Others

PMID	Journal	Published Date	Author	Title
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20203298	Arterioscler. Thromb. Vasc. Biol.	2010	Samokhin AO et al.	Cholate-containing high-fat diet induces the formation of multinucleated giant cells in atherosclerotic plaques of apolipoprotein E-/- mice.
19074988	Diabetes	2009	Delibegovic M et al.	Liver-specific deletion of protein-tyrosine phosphatase 1B (PTP1B) improves metabolic syndrome and attenuates diet-induced endoplasmic reticulum stress.
18801708	J. Chromatogr. B Analyt. Technol. Biomed. Life Sci.	2008	Alnouti Y et al.	Quantitative-profiling of bile acids and their conjugates in mouse liver, bile, plasma, and urine using LC-MS/MS.
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26714852	Am. J. Physiol. Endocrinol. Metab.	2016	Zietak M and Kozak LP	Bile acids induce uncoupling protein 1-dependent thermogenesis and stimulate energy expenditure at thermoneutrality in mice.
26683664	Am. J. Pathol.	2016	McMillin M et al.	Bile Acid Signaling Is Involved in the Neurological Decline in a Murine Model of Acute Liver Failure.
25196788	J Pharm Sci	2014	Vivian D et al.	Design and evaluation of a novel trifluorinated imaging agent for assessment of bile acid transport using fluorine magnetic resonance imaging.