stearic acid is a lipid of Fatty Acyls (FA) class. Stearic acid is associated with abnormalities such as Helminthiasis, Exanthema, Chronic disease, Obesity and Dyslipidemias. The involved functions are known as acyltransferase activity, Mutation, Cell division, cell fate and Fatty Acid Metabolism. Stearic acid often locates in membrane fraction, Mouse Liver, Membrane, Body tissue and Endoplasmic reticulum, membrane. The associated genes with stearic acid are Homologous Gene, ACLY gene, Transgenes, FATE1 gene and Alleles. The related lipids are Lysophospholipids, Stearic acid, Fatty Acids, cis-vaccenic acid and Phosphatidylserines. The related experimental models are Knock-out.
PMID | Journal | Published Date | Author | Title |
---|---|---|---|---|
9484999 | Arterioscler. Thromb. Vasc. Biol. | 1998 | Turpeinen AM et al. | Similar effects of diets rich in stearic acid or trans-fatty acids on platelet function and endothelial prostacyclin production in humans. |
9555866 | Arterioscler. Thromb. Vasc. Biol. | 1998 | Mennen L et al. | Factor VIIa response to a fat-rich meal does not depend on fatty acid composition: a randomized controlled trial. |
9643360 | J. Lipid Res. | 1998 | Aarsland A and Wolfe RR | Hepatic secretion of VLDL fatty acids during stimulated lipogenesis in men. |
11481404 | J. Nutr. | 2001 | Gupta SV and Khosla P | Palmitic and stearic acids similarly affect plasma lipoprotein metabolism in cynomolgus monkeys fed diets with adequate levels of linoleic acid. |
11430415 | FEMS Microbiol. Lett. | 2001 | Radwan SS et al. | Effects of lipids on n-alkane attenuation in media supporting oil-utilizing microorganisms from the oily Arabian Gulf coasts. |
12421851 | J. Nutr. | 2002 | Treadwell RM et al. | Glyceride stearic acid content and structure affect the energy available to growing rats. |
12663272 | Am. J. Clin. Nutr. | 2003 | Sanders TA et al. | Influence of triacylglycerol structure on the postprandial response of factor VII to stearic acid-rich fats. |
10584037 | Am. J. Clin. Nutr. | 1999 | Connor WE | Harbingers of coronary heart disease: dietary saturated fatty acids and cholesterol. Is chocolate benign because of its stearic acid content? |
10787438 | J. Lipid Res. | 2000 | Schmider W et al. | Transport of heptafluorostearate across model membranes. Membrane transport of long-chain fatty acid anions I. |
14652360 | J. Nutr. | 2003 | Baer DJ et al. | Stearic acid absorption and its metabolizable energy value are minimally lower than those of other fatty acids in healthy men fed mixed diets. |
19783644 | Plant Physiol. | 2009 | Clemente TE and Cahoon EB | Soybean oil: genetic approaches for modification of functionality and total content. |
17556683 | Am. J. Clin. Nutr. | 2007 | Berry SE et al. | The solid fat content of stearic acid-rich fats determines their postprandial effects. |
16317124 | J. Nutr. | 2005 | Thijssen MA et al. | Stearic, oleic, and linoleic acids have comparable effects on markers of thrombotic tendency in healthy human subjects. |
16990414 | Clin. Chem. | 2006 | Kazmierczak SC et al. | Electron spin resonance spectroscopy of serum albumin: a novel new test for cancer diagnosis and monitoring. |
17056791 | J. Nutr. | 2006 | Rasmussen HE et al. | Reduction in cholesterol absorption is enhanced by stearate-enriched plant sterol esters in hamsters. |
16155261 | Am. J. Clin. Nutr. | 2005 | Thijssen MA and Mensink RP | Small differences in the effects of stearic acid, oleic acid, and linoleic acid on the serum lipoprotein profile of humans. |
18596092 | J. Virol. | 2008 | Kordyukova LV et al. | S acylation of the hemagglutinin of influenza viruses: mass spectrometry reveals site-specific attachment of stearic acid to a transmembrane cysteine. |
22628618 | J. Lipid Res. | 2012 | Masuda M et al. | Activating transcription factor 4 regulates stearate-induced vascular calcification. |
18387886 | J. Lipid Res. | 2008 | Lockridge JB et al. | Bioinformatic profiling of the transcriptional response of adult rat cardiomyocytes to distinct fatty acids. |
19357638 | Mol. Syst. Biol. | 2009 | Atherton HJ et al. | Metabolomics of the interaction between PPAR-alpha and age in the PPAR-alpha-null mouse. |
18812595 | J. Lipid Res. | 2009 | Kratzer A et al. | Synthetic LXR agonist attenuates plaque formation in apoE-/- mice without inducing liver steatosis and hypertriglyceridemia. |
26739624 | Toxicol. Appl. Pharmacol. | 2016 | Michaut A et al. | A cellular model to study drug-induced liver injury in nonalcoholic fatty liver disease: Application to acetaminophen. |
23880231 | Cancer Prev Res (Phila) | 2013 | Subbaramaiah K et al. | Dietary polyphenols suppress elevated levels of proinflammatory mediators and aromatase in the mammary gland of obese mice. |
22679004 | Am. J. Physiol. Gastrointest. Liver Physiol. | 2012 | Bederman I et al. | Altered de novo lipogenesis contributes to low adipose stores in cystic fibrosis mice. |
21995961 | Am. J. Physiol. Gastrointest. Liver Physiol. | 2012 | Kakisaka K et al. | Mechanisms of lysophosphatidylcholine-induced hepatocyte lipoapoptosis. |
21586336 | Biochim. Biophys. Acta | 2012 | Schreiber R et al. | Retinyl ester hydrolases and their roles in vitamin A homeostasis. |
20006369 | Virology | 2010 | Kordyukova LV et al. | Site-specific attachment of palmitate or stearate to cytoplasmic versus transmembrane cysteines is a common feature of viral spike proteins. |
19945403 | Cell Metab. | 2009 | Hoppa MB et al. | Chronic palmitate exposure inhibits insulin secretion by dissociation of Ca(2+) channels from secretory granules. |
18718999 | Am. J. Physiol. Gastrointest. Liver Physiol. | 2008 | Labonté ED et al. | Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice. |
18054317 | Cell Metab. | 2007 | Miyazaki M et al. | Hepatic stearoyl-CoA desaturase-1 deficiency protects mice from carbohydrate-induced adiposity and hepatic steatosis. |
17244890 | Am. J. Physiol. Renal Physiol. | 2007 | Feldkamp T et al. | Alleviation of fatty acid and hypoxia-reoxygenation-induced proximal tubule deenergization by ADP/ATP carrier inhibition and glutamate. |
15722436 | Biophys. J. | 2005 | Citadini AP et al. | EPR studies of chlorocatechol 1,2-dioxygenase: evidences of iron reduction during catalysis and of the binding of amphipatic molecules. |
27371261 | J. Lipid Res. | 2016 | Sun Y et al. | Plasma fatty acids, oxylipins, and risk of myocardial infarction: the Singapore Chinese Health Study. |
26701797 | J. Nutr. | 2016 | Fretts AM et al. | Associations of Plasma Phospholipid SFAs with Total and Cause-Specific Mortality in Older Adults Differ According to SFA Chain Length. |
25527759 | Am. J. Clin. Nutr. | 2015 | Ma W et al. | Prospective association of fatty acids in the de novo lipogenesis pathway with risk of type 2 diabetes: the Cardiovascular Health Study. |