1,2-Dioleoyl-sn-Glycero-3-Phosphocholine

1,2-Dioleoyl-sn-Glycero-3-Phosphocholine is a lipid of Glycerophospholipids (GP) class. 1,2-dioleoyl-sn-glycero-3-phosphocholine is associated with abnormalities such as Exanthema, Renal tubular disorder, Nodule, Gigantism and Mycoses. The involved functions are known as Lysis, Encapsulation, Process, Uptake and Flow or discharge. 1,2-dioleoyl-sn-glycero-3-phosphocholine often locates in Cytoplasmic matrix, Endosomes, soluble, Endoplasmic Reticulum and Membrane. The associated genes with 1,2-Dioleoyl-sn-Glycero-3-Phosphocholine are P4HTM gene, synthetic peptide, BCAR1 gene, PCNA gene and CNTNAP1 gene. The related lipids are Liposomes, 1,2-oleoylphosphatidylcholine, 1,2-distearoylphosphatidylethanolamine, Butanols and Cardiolipins. The related experimental models are Mouse Model and Xenograft Model.

References related to functions published in Others


PMIDJournalPublished DateAuthorTitle
9012343Science1997Rädler JO et al.Structure of DNA-cationic liposome complexes: DNA intercalation in multilamellar membranes in distinct interhelical packing regimes.
9651248Science1998Koltover I et al.An inverted hexagonal phase of cationic liposome-DNA complexes related to DNA release and delivery.
10430866Proc. Natl. Acad. Sci. U.S.A.1999Weiss C et al.Domain structure and lipid interaction of recombinant yeast Tim44.
11518756J. Lipid Res.2001Zucker SD et al.Localization of bilirubin in phospholipid bilayers by parallax analysis of fluorescence quenching.
12198149EMBO J.2002Or E et al.Dissociation of the dimeric SecA ATPase during protein translocation across the bacterial membrane.
11375932EMBO Rep.2001Ridder AN et al.Anionic lipids stimulate Sec-independent insertion of a membrane protein lacking charged amino acid side chains.
11121015Proc. Natl. Acad. Sci. U.S.A.2000Koltover I et al.DNA condensation in two dimensions.
11714813J. Immunol.2001Chikh GG et al.Efficient delivery of Antennapedia homeodomain fused to CTL epitope with liposomes into dendritic cells results in the activation of CD8+ T cells.
20713738Proc. Natl. Acad. Sci. U.S.A.2010Lundbaek JA et al.Amphiphile regulation of ion channel function by changes in the bilayer spring constant.
21097953Protein Eng. Des. Sel.2011Debnath DK et al.The role of membrane properties in Mistic folding and dimerisation.
21421858Clin. Cancer Res.2011Chakravarty D et al.Therapeutic targeting of PELP1 prevents ovarian cancer growth and metastasis.
19509339Proc. Natl. Acad. Sci. U.S.A.2009Traaseth NJ et al.Structure and topology of monomeric phospholamban in lipid membranes determined by a hybrid solution and solid-state NMR approach.
20368457Proc. Natl. Acad. Sci. U.S.A.2010Heinrich M et al.Dynamic sorting of lipids and proteins in membrane tubes with a moving phase boundary.
19850632Clin. Chem.2009Chalbot S et al.Cerebrospinal fluid secretory Ca2+-dependent phospholipase A2 activity is increased in Alzheimer disease.
20430760Cancer Res.2010Tanaka T et al.Sustained small interfering RNA delivery by mesoporous silicon particles.
20504804J R Soc Interface2011Zhang HY and Hill RJConcentration dependence of lipopolymer self-diffusion in supported bilayer membranes.
18413840Clin. Cancer Res.2008Verma A et al.Therapeutic significance of elevated tissue transglutaminase expression in pancreatic cancer.
16061675Cancer Res.2005Landen CN et al.Therapeutic EphA2 gene targeting in vivo using neutral liposomal small interfering RNA delivery.
16914580Clin. Cancer Res.2006Halder J et al.Focal adhesion kinase targeting using in vivo short interfering RNA delivery in neutral liposomes for ovarian carcinoma therapy.
21876041Antimicrob. Agents Chemother.2011Paiva AD et al.Role of lipid II and membrane thickness in the mechanism of action of the lantibiotic bovicin HC5.
23093677Proc. Natl. Acad. Sci. U.S.A.2012Bouvrais H et al.Intrinsic reaction-cycle time scale of Na+,K+-ATPase manifests itself in the lipid-protein interactions of nonequilibrium membranes.
24707049Proc. Natl. Acad. Sci. U.S.A.2014Quazi F and Molday RSATP-binding cassette transporter ABCA4 and chemical isomerization protect photoreceptor cells from the toxic accumulation of excess 11-cis-retinal.
24344297Proc. Natl. Acad. Sci. U.S.A.2014Chen D and Santore MMLarge effect of membrane tension on the fluid-solid phase transitions of two-component phosphatidylcholine vesicles.
21957230J. Natl. Cancer Inst.2011Nick AM et al.Silencing of p130cas in ovarian carcinoma: a novel mechanism for tumor cell death.
24631490Free Radic. Biol. Med.2014Jiang J et al.Designing inhibitors of cytochrome c/cardiolipin peroxidase complexes: mitochondria-targeted imidazole-substituted fatty acids.
26246573J. Virol.2015Dick RA et al.Hydrodynamic and Membrane Binding Properties of Purified Rous Sarcoma Virus Gag Protein.
25658342Essays Biochem.2015Ackerman DG and Feigenson GWLipid bilayers: clusters, domains and phases.
25825736Proc. Natl. Acad. Sci. U.S.A.2015Ando J et al.Sphingomyelin distribution in lipid rafts of artificial monolayer membranes visualized by Raman microscopy.
25589571J R Soc Interface2015Barnoud J et al.C₆₀ fullerene promotes lung monolayer collapse.
25201964Proc. Natl. Acad. Sci. U.S.A.2014Nelson SR et al.Motor coupling through lipid membranes enhances transport velocities for ensembles of myosin Va.
24647907J R Soc Interface2014Kent B et al.Localization of trehalose in partially hydrated DOPC bilayers: insights into cryoprotective mechanisms.