Aminoadipic acid

Aminoadipic acid is a lipid of Fatty Acyls (FA) class. Aminoadipic acid is associated with abnormalities such as Diabetes and Proliferative retinopathy NOS. The involved functions are known as Uptake, Process, lysine catabolism, Pressure- physical agent and Proteolysis. Aminoadipic acid often locates in Protoplasm, Chromosomes, Astrocytic, Basal lamina and Cytoplasmic matrix. The associated genes with Aminoadipic acid are Homologous Gene, Excitatory Amino Acids, allysine, Diaminopimelic Acid and Gene Clusters.

References related to functions published in Others


PMIDJournalPublished DateAuthorTitle
9721323J. Bacteriol.1998Pérez-Llarena FJ et al.The pcd gene encoding piperideine-6-carboxylate dehydrogenase involved in biosynthesis of alpha-aminoadipic acid is located in the cephamycin cluster of Streptomyces clavuligerus.
10074061J. Bacteriol.1999Kobashi N et al.Aspartate kinase-independent lysine synthesis in an extremely thermophilic bacterium, Thermus thermophilus: lysine is synthesized via alpha-aminoadipic acid not via diaminopimelic acid.
12509419J. Biol. Chem.2003Hijarrubia MJ et al.Domain structure characterization of the multifunctional alpha-aminoadipate reductase from Penicillium chrysogenum by limited proteolysis. Activation of alpha-aminoadipate does not require the peptidyl carrier protein box or the reduction domain.
10613839Genome Res.1999Nishida H et al.A prokaryotic gene cluster involved in synthesis of lysine through the amino adipate pathway: a key to the evolution of amino acid biosynthesis.
20720223Invest. Ophthalmol. Vis. Sci.2011Shen W et al.Submacular DL-alpha-aminoadipic acid eradicates primate photoreceptors but does not affect luteal pigment or the retinal vasculature.
19850833Invest. Ophthalmol. Vis. Sci.2010Johnson TV et al.Identification of barriers to retinal engraftment of transplanted stem cells.
19854833J. Biol. Chem.2009Fan X et al.Mechanism of lysine oxidation in human lens crystallins during aging and in diabetes.
26400963J. Nutr.2015Ross AB et al.Herring and Beef Meals Lead to Differences in Plasma 2-Aminoadipic Acid, β-Alanine, 4-Hydroxyproline, Cetoleic Acid, and Docosahexaenoic Acid Concentrations in Overweight Men.
19211881J. Neurosci.2009Wang YF and Hatton GIAstrocytic plasticity and patterned oxytocin neuronal activity: dynamic interactions.