Tacrolimus is a lipid of Polyketides (PK) class. Tacrolimus is associated with abnormalities such as Renal glomerular disease. The involved functions are known as inhibitors, Fungicidal activity, Metabolic Inhibition, Excretory function and Dephosphorylation. Tacrolimus often locates in Hepatic, Mitochondrial matrix and Inner mitochondrial membrane. The associated genes with Tacrolimus are RHOA gene and BGN gene.
|12493747||J. Biol. Chem.||2003||Barat C and Tremblay MJ||Treatment of human T cells with bisperoxovanadium phosphotyrosyl phosphatase inhibitors leads to activation of cyclooxygenase-2 gene.|
|15280438||J. Pharmacol. Exp. Ther.||2004||Watabe M and Nakaki T||Rotenone induces apoptosis via activation of bad in human dopaminergic SH-SY5Y cells.|